By means of yeast (Saccharomyces cerevisiae) two-hybrid screening, we identified basic helix-loop-helix transcription factor05 (bHLH05) as an interacting partner of MYB51, the key regulator of indolic glucosinolates (GSLs) in Arabidopsis (Arabidopsis thaliana). Furthermore, we show that bHLH04, bHLH05, and bHLH06/MYC2 also interact with other R2R3-MYBs regulating GSL biosynthesis. Analysis of b...

Glycosphingolipids (GSLs) are neoplastic and normal/cancer stem cell markers and GSL/cholesterol-containing membrane rafts are increased in cancer cell plasma membranes. We define a novel means by which cancer cells can restrict tumor-associated GSL immunoreactivity. The GSL-cholesterol complex reorients GSL carbohydrate to a membrane parallel, rather than perpendicular conformation, largely un...

The structurally unique glucosinolate (GSL), 4-(cystein-S-yl)butyl GSL, was identified in the leaves of hydroponically-grown rocket salad (Eruca sativa Mill.). Its electrospray ionization mass spectrometry (ESI-MS)/MS spectrum indicated that this unusual GSL had a molecular weight of 414 as a desulfo (DS)-GSL, and a molecular formula of C(14)H(25)N(2)O(8)S(2) based on its negative ion matrix-as...

Great Salt Lake (GSL) is the largest salt lake in the western hemisphere, the fourthlargest terminal lake in the world. The elevation of GSL has critical effect on the people who live nearby and their properties. It is crucial to build an exact model of GSL elevation time series in order to predict the GSL elevation precisely. Although some models, such as ARIMA or FARIMA (fractional auto-regre...

Glucosinolates (GSLs) in the plant order of the Brassicales are sulfur-rich secondary metabolites that harbor antipathogenic and antiherbivory plant-protective functions and have medicinal properties, such as carcinopreventive and antibiotic activities. Plants repress GSL biosynthesis upon sulfur deficiency (-S); hence, field performance and medicinal quality are impaired by inadequate sulfate ...

Previously, we showed that the addition of human erythrocyte glycosphingolipids (GSLs) to nonhuman CD4(+) or GSL-depleted human CD4(+) cells rendered those cells susceptible to HIV-1 envelope glycoprotein-mediated cell fusion. Individual components in the GSL mixture were isolated by fractionation on a silica-gel column and incorporated into the membranes of CD4(+) cells. GSL-supplemented targe...

In this paper we introduce the characteristics of the educational platform that is being developed within the SYNENNOESE project. The platform integrates avatar and animation technologies, exploiting electronic linguistic resources of the Greek Sign Language (GSL), in order to provide a Greek-to-GSL conversion tool that allows to construct, store and maintain educational material in GSL. Beside...

Glucosinolates (GSLs) play an important role in plants as direct mediators of biotic and abiotic stress responses. Recent work is beginning to show that the GSLs can also inducing complex defense and growth networks. However, the physiological significance of these GSL-induced responses and the molecular mechanisms by which GSLs are sensed and/or modulate these responses are not understood. To ...

This paper reports on research and development work for the implementation of a Greek to Greek Sign Language (GSL) conversion tool, integrated into an educational platform that addresses needs of teaching GSL grammar, exploiting avatar technologies for the representation of linguistic message articulated in the 3D space. The Greek to GSL conversion engine that supports the platform is composed ...

In this paper we present the creation and presentation of dynamic linguistic resources of Greek Sign Language (GSL). The resources feed the development of an educational multitask platform within the SYNENNOESE project for the teaching of GSL. The platform utilizes standard virtual character (VC) animation technologies for the synthesis of sign sequences/streams, exploiting digital linguistic r...