Visceral leishmaniasis (VL), the second-most-serious parasitic illness after malaria, is currently endemic in more than 88 countries. Need for new anti-leishmanial compounds being taken into consideration by researchers due to resistance and lack of effective vaccinations. This research was conducted find out about effect artemisinin (ART). ART examined vitro promastigotes stages ex vivo amasti...

The nasal decongestants oxymetazoline and xylometazoline are frequently used in the topical treatment of rhinitis and sinusitis. As nitric oxide (NO) is thought to play a role in inflammation of the upper respiratory tract, the aim of this study was to examine the in vitro effects of these compounds on the activity and the expression of NO producing enzymes, including the inducible form of NO s...

A review of using Griess Reaction method to determine nitric oxide production in biological systems.

Aim. To assess laboratory markers of hemodynamic status in patients with moderate to severe COVID-19. Materials and Methods. Here we examined 15 COVID-19 16 critically ill patients. The control group consisted 20 healthy volunteers. levels endothelin-1, brain natriuretic peptide (BNP), N-terminal pro-brain (NT-proBNP) were measured by enzyme-linked immunosorbent assay. amounts nitrites (NO 2 ) ...

Abstract Several influenza pandemics have impacted our life, each with variable prevalence and severity. In a search for natural antivirals, further phytochemical investigation of Gardenia latifolia Aiton, Rubiaceae, was conducted. As result, five structurally diverse glycosides were isolated, offering valuable chemotaxonomic data. Using the crystal violet technique, three isolates, canthoside ...

Objective: To investigate the anti-inflammatory effects of total flavonoids from Saussurea involucrata on lipopolysaccharides (LPS)-stimulated murine RAW264.7 macrophages and explore its underlying mechanism action. Methods: Total were extracted using chromatographic column method. Cell viability was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay. The producti...

Astaxanthin and tocotrienols, known as antioxidants derived from natural compounds shown to have anti-inflammatory properties. This study aims investigate the effects of a combination astaxanthin extracted Hematococcus pluvialis microalga palm tocotrienols rich-fraction (TRF) on inflammatory reaction in lipopolysaccharide (LPS)-stimulated mouse RAW 264.7 macrophages cells. MTT assay was used te...