A green and efficient protocol for the synthesis of 3,3,6,6-tetramethyl-9-aryl-1,8-dioxooctahydroxanthene derivatives via cyclocondensation of 5,5-dimethyl-1,3-cyclohexanedione and aromatic aldehydes in the presence of catalytic amount of 10-molybdo-2-vanadophosphoric acid under solvent-free conditions has been described. The 10-molybdo-2-vanadophosphoric acid was prepared and characterized by ...

One of the liabilities of the Apc(Min) mouse as a model for colon cancer is its lack of a robust tumor response in the large bowel. In our protocol, we treated the Apc(Min) mouse with azoxymethane, a colon-selective carcinogen. This protocol induced a 4-fold increase in the number of colon tumors. We utilized this protocol to investigate the possible mechanisms of inhibition of colorectal carci...

a highly efficient, simple and clean solvent-free protocol for the synthesis of polyhydroquinolines is described. the one-pot multi-component condensation reaction between arylaldehydes, dimedone (5,5-dimethylcyclohexane-1,3-dione), β-ketoesters and ammonium acetate in the presence of catalytic amount of (2.5 mol%) melamine trisulfonic acid (mtsa) as a recyclable, green and attractive sulfonic ...

     In this study an easy, green, efficient and simple approach is reported for the synthesis of some benzothiazole-, benzimidazole- and benzoxazole-2-thiolderivatives. The proposed approach employs the reaction of corresponding aromatic amine with potassium isopropyl xanthate (Z11) in the presence of copper sulfate (CuSO4) as a catalyst under conventional heating and ultrasonic irr...

An one-pot method has been developed for the synthesis of azo dyes via sequential diazotization–diazo coupling of aromatic amines with coupling agents at room temperature in the presence of Bi(NO3)3. 5H2O. Short reaction times, high yields, a clean process, simple methodology, easy work-up and green ‎conditions are advantages of this protocol.‎

An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.

an one-pot method has been developed for the synthesis of azo dyes via sequential diazotization–diazo coupling of aromatic amines with coupling agents at room temperature in the presence of bi(no3)3. 5h2o. short reaction times, high yields, a clean process, simple methodology, easy work-up and green ‎conditions are advantages of this protocol.‎

An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol.

Condensation reaction of chalcones with malononitrile and ammonium acetate in the presence of the green nano-modified SBA-15 affords the corresponding 2-amino-3-cyanopyridine derivatives in excellent yield. This approaches claimed to be an environment friendly protocol as it afforded some advantages such as excellent yields and cleaner reaction.