This study examined the effect of Testofen, a specialised Trigonella foenum-graecum seed extract on the symptoms of possible androgen deficiency, sexual function and serum androgen concentrations in healthy aging males. This was a double-blind, randomised, placebo-controlled trial involving 120 healthy men aged between 43 and 70 years of age. The active treatment was standardised Trigonella foe...

Trigonella foenum-graecum L. (Fenugreek) is an important plant of the Leguminosae family known to have medicinal properties. However, fraction based antiquorum sensing and antibiofilm activities have not been reported from this plant. In the present study T. foenum-graecum seed extract was sequentially fractionated and sub-MICs were tested for above activities. The methanol fraction of the extr...

background: studies have emphasized the effect of trigonella foenum-graecum extract on the reduction of pain and inflammation. objective: in this research we investigated the mechanisms of trigonella foenum-graecum extract in reducing pain and inflammation induced by formalin. methods: male albino mice (weight 20 - 25 g) were evaluated through the injection of 2 microliters of formalin to the p...

The objective of the study was to search for the appropriate herbal extracts by comparative analysis of their estrogenic and cytotoxic activities. Some potentially estrogenic activity of herbal extracts in the management of female disorder symptoms was investigated by E-screen assay. The extracts having a promising activity were further evaluated in vitro for their cytotoxic activity. Of 13 her...

Background: The main goals of our study were as follows: (1) to investigate whether the methanolic extract of the new cultivar (Gürarslan) of Trigonella foenum graecum L. seeds exhibit antiproliferative effects on the HeLa human cervix carcinoma, Mat-LyLu rat prostate carcinoma and 3T3 embryonic mouse fibroblast cell lines, (2) to determine how mitosis and DNA synthesis are affected in cancer c...

The aim of the study was to evaluate the effect of Trigonella foenum-graecum (fenugreek) seed extract on sex hormones and sexual function in healthy menstruating women who reported low sexual drive. This short term, single site, double blind, randomised, placebo-controlled study was conducted on 80 women, aged 20 to 49 years. Participants were randomised to either an oral dose of a standardised...

In the present study the amount of three important flavonols (kaempferol, quercetin, myricetin) and five phenolic acids (gallic acid, ferulic acid, cinnamic acid, vanillic acid and caffeic acid) were determined from four medicinally important indigenous plants like Euphorbia tirucalli, Trigonella foenum-graecum, Cyperus rotundus and Rheum emodi. Methanolic extracts of native parts and gemmo-mod...

Trigonella foenum-graecum (TG) is one of the important medicinal plant which have antioxidant, antidiabetic, antilipidemic and antimicrobial properties. The main aim this study was to evaluate free radical scavenging properties, total phenolic, flavonoid content phytochemical screening foenum-graecum. antioxidant activities like 2,2-diphenylpicrylhydrazyl (DPPH), hydroxyl activity, hydrogen per...

The use of bioactive tanniniferous plants seems a promising alternative to control infections parasitic nematodes of the gastro intestinal tract in small ruminants. Both in vitro and in vivo studies, have confirmed the anthelmintic properties of several forage legumes, or tropical and browse plants. The aim of the present study was to evaluate the in vitro anthelmintic (AH) effect of 3 Tunisian...