Import of newly synthesized PTS1 proteins into the peroxisome requires the PTS1 receptor (Pex5p), a predominantly cytoplasmic protein that cycles between the cytoplasm and peroxisome. We have identified Pex13p, a novel integral peroxisomal membrane from both yeast and humans that binds the PTS1 receptor via a cytoplasmically oriented SH3 domain. Although only a small amount of Pex5p is bound to...

nature neuroscience • volume 2 no 3 • march 1999 The involvement of the hippocampal formation in learning has been recognized for decades1,2, but the cellular mechanisms underlying this association remain enigmatic. The hippocampal formation produces new neurons throughout adulthood in many vertebrates, from birds to primates3–8; however, although the number of neurons produced is high, the fun...

Peroneal tendon and retinacular pathology contributes to chronic lateral ankle instability. The “gold standard” surgical treatment for chronic lateral ankle instability has been the BroströmGould procedure with its modifications. An ankle arthroscopy is an adjuvant procedure to address any intra-articular pathology. We review our results of two study groups. The first group underwent an ankle a...

We present a combinatorial proof of the equivalence between a formula of MacMahon and a formula of Gould using free 2-Motzkin paths, and give a generalization for a formula asked by Gould as well.