The obligate intracellular Gram-negative bacterium Chlamydia abortus is one of the causative agents of abortion and fetal loss in sheep, goats, and cattle in many countries. It also affects the reproductivity of yaks (Bos grunniens). This study reports the whole-genome sequence of Chlamydia abortus strain GN6, which was isolated from aborted yak fetus in Qinghai-Tibetan Plateau, China.

OBJECTIVE To create genetically modified goat as a biopharming source of recombinant human lacotoferrin (hLF) with transcription activator-like effector nucleases. METHODS TALENs and targeting vector were transferred into cultured fibroblasts to insert hLF cDNA in the goat beta-lactoglobulin (BLG) locus with homology-directed repair. The gene targeted efficiency was checked using sequencing a...

BACKGROUND AND OBJECTIVES Brucella, causative of brucellosis, has some potential virulence factors involved in Brucella replication and its strategies to circumvent the immune response. One of them is the virB gene that encodes the type IV secretion system proteins (T4SS) involved in intracellular replication of organism. Brucella virulence factor A (bvfA), and urease (ure) has also been descri...

infection by toxoplasma gondii is widespread inhumans and many other species of warm-blooded animals. it can cause significant morbidity and mortality in the developing fetus and in immunocompromised individuals,including humans with acquired immunodeficiency syndrome (aids) or submitted to cancer chemotherapy.among livestock, sheep and goat are more widely infected with t. gondii. this parasit...

Fetal hypophysectomy performed between 97 and 130 days of gestation caused a significant (P is less than 0.005) prolongation of pregnancy in 5 goats in which every fetus was treated. Three of these goats gave birth spontaneously. Sham surgery or hypophysectomy of one fetus of twins had no effect on gestation length. Hypophysectomized kids, delivered after prolonged pregnancy, were significantly...

The capability of the recently emerged European strain of bluetongue virus serotype 8 (BTV-8) to cross the ruminant placenta has been established in experimental and field studies in both sheep and cattle. Seroprevalence rates in goats in North-Western Europe were high during the recent outbreak of BTV-8; however the capability of the virus to infect goats through the transplacental route has n...

Pasteurization or boiling of milk would eliminate brucellosis except in those whose work brings them in contact with infected animals or their carcases, and laboratory workers. Complete eradication of the disease in humans depends on its eradication in animals. This has been achieved in Norway as a result of laws which stated that aborting animals must be reported and tested, and that the owner...

Blood sera samples from 99 clinically healthy goats, 230 sheep and 171 rams were investigated by CF test and indirect ELISA. In case of goats, 3.03% seroprevalence was detected, in sheep it was 3.04%, whereas, in case of rams seroprevalence was 0% by using complement fixation test. Using iELISA in the same groups the seroprevalences observed were, 24.24% in goats, 11.30% in sheep and 5.30% in r...

In the routine typing of Br. melitensis isolated from goats' milk in Malta, it was found that I I of 46 strains gave entirely negative reactions to agglutination tests in which both mono-specific Br. abortus a nd mono-specific Br. melitensis sera were used: in all other respects these strains appeared to be typical Br. melitensis. All the strains were isolated on albimi agar containing antibiot...