نتایج جستجو برای: glycomics
تعداد نتایج: 801 فیلتر نتایج به سال:
Chemical glycomics uses synthetic chemistry to procure defined carbohydrate molecules to study the glycans involved in many functions in the living cell. Based on an automated synthesis platform, a host of synthetic tools including carbohydrate microarrays has been developed. These tools have been employed to dissect carbohydrate-copolymer interactions. Basic research in the glycomics arena is ...
Recent progress in mass spectrometry has led to new challenges in glycomics, including the development of rapid glycan enrichment techniques. A facile technique for exploration of a carbohydrate-related biomarker is important because proteomics research targets glycosylation, a posttranslational modification. Here we report an “all-in-one” protocol for high throughput clinical glycomics. This n...
1 Center of Bioinformatics (COBI), Key Laboratory for NeuroInformation of Ministry of Education, University of Electronic Science and Technology of China, Chengdu 610054, China 2Department of Chemistry and Alberta Glycomics Centre, University of Alberta, Edmonton, AB, Canada T6G 2G2 3National Engineering Laboratory for Druggable Gene and Protein Screening, Northeast Normal University, Changchun...
Glycomics is an international initiative aimed to understand the structure and function of the glycans from a given type of cell, tissue, organism, kingdom or even environment, as found under certain conditions. Glycomics is one of the latest areas of intense biological research. Glycans of marine sources are unique in terms of structure and function. They differ considerably from those of terr...
Glycomics is a discipline of biology that deals with the structure and function of glycans (or carbohydrates). Analytical techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) are having a significant impact on the field of glycomics. However, effective progress in glycomics research requires collaboration between laboratories to share experimental data, structural info...
MOTIVATION Over the last decades several glycomics-based bioinformatics resources and databases have been created and released to the public. Unfortunately, there is no common standard in the representation of the stored information or a common machine-readable interface allowing bioinformatics groups to easily extract and cross-reference the stored information. RESULTS An international group...
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. An increased molecular understanding of the CRC pathology is warranted to gain insights into the underlying molecular and cellular mechanisms of the disease. Altered protein glycosylation patterns are associated with most diseases including malignant transformation. Recent advances in mass spectrometry and bioinformatics ha...
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