Glycoconjugates [protein bound hexose, protein bound hexosamine, total sialic acid and fucose] play a pivotal role in neoplastic transformation if they are abnormally expressed. The protective effect of Enicostemma littorale leaves on cell surface abnormalities was analyzed by measuring the status of the above said glycoconjugates during 7,12dimethylbenz(a) anthracene (DMBA) induced hamster buc...

The floor plate is a small group of cells located at the ventral midline of neural tube. During early neurogenesis the floor plate plays critical role (s) in differentiation of ventral portion of neural tube.The purpose of this study was to determine the distribution of glycoconjugates in floor plate as well as underlying mesoderm (notochord) and their inductive activities in mouse embryos.Form...

The biosynthesis of corneal epithelial proteins and glycoconjugates and their response to vitamin A were measured in vitamin A-deficient and normal rats. The synthesis of specific high-molecular-weight epithelial glycoconjugates was directly related to the levels of vitamin A administered. Protein synthesis, however, remained unaltered. Since vitamin A is known to reverse the keratinization pro...

introduction: it is well known that glycoconjugates on the cell surface of embryonic cells as well as extracellular matrix (ecm) are involved in many developmental phenomena including cell differentiation and maturation. these molecular events have not received proper attention during pituitary cell differentiation. the purpose of this study was to investigate glycoconjugate distribution on cel...

Glycoconjugates on the photoreceptor cell surfaces and in the interphotoreceptor matrix (IPM) are involved in a variety of cell functions. The O-linked glycoconjugates, seen in the filaments of IPM by electron microscopy,’ may connect the neural retina with the retinal pigment epithelium (RPE) in the subretinal space.’ These O-linked glycoconjugates are found on the surfaces of both cone and ro...

The interactions of cell surface carbohydrates as well as of soluble glycoconjugates with their receptor proteins rule fundamental processes in cell biology. One of the supramolecular principles underlying and regulating carbohydrate recognition is multivalency. Many multivalent glycoconjugates have therefore been synthesized to study multivalency effects operative in glycobiology. This review ...

background: the aim of this research was to study the distribution and changes of glycoconjugates particularly their terminal sugars by using lectin histochemistry during mouse spinal cord development. methods: formalin-fixed sections of mouse embryo (10-16 fetal days) were processed for lectin histochemical method. in this study, two groups of horseradish peroxidase-labeled specific lectins we...

introduction: during early neural tube formation, the notochord is essential for the induction of ectoderm and for the subsequent differentiation of the neuroepithelium forming diverse cell types in the neural tube. due to the key role of the glycoconjugates in many developmental events, the early distribution of these molecules in early notochordal interaction with adjacent tissues were studie...