The antioxidant potential of foods plays a vital role in counteracting oxidative stress and its consequences the body. Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) are primary line defence against cellular damage caused by reactive oxygen species (ROS). Glutathione is considered to be most for body because changes during increase risk CVD. dietary capacity supporting...

Glutathione peroxidase (GPX) is a critical antioxidant selenoenzyme in organisms that protects cells against oxidative damage by catalyzing the reduction of hydroperoxides by glutathione (GSH). Thus, some GPX mimics have been generated because of their potential therapeutic value. The generation of a semisynthetic selenoenzyme with peroxidase activity, which matches the catalytic efficiencies o...

Oxidative stress is common in several human and veterinary conditions it associated to alteration of the glutathione peroxidase (GPx) level. GPx an enzyme present erythrocytes, kidney, liver has a role protecting against oxidative damage. In this randomised double-blinded control trial on healthy dogs, we findings indicating that administration for total 35 days supplement containing S-acetyl-g...

There is a requirement for cellular defense against excessive peroxynitrite generation to protect against DNA strand breaks and mutations and against interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine. Here, we demonstrate a role of selenium-containing enzymes catalyzing peroxynitrite reduction using glutathione peroxidase (GPx) as...

Reproductive failure is regarded as a problem in the breeding of beef cattle indicated by low calving rate, conception longer periods interval, and neonatal mortality. Selenium deficiency may lead to non-infectious reproduction disorder ruminants. The purpose this review evaluate role selenium preventing cattle. In process, required for cellular respiration, oxidation, DNA RNA replication, inte...

Submit Manuscript | http://medcraveonline.com Abbreviations: ANOVA: Analysis of Variance; CAT: Catalase; GSH: Glutathione; GSSG: Oxidized Glutathione; GPx: Glutathione Peroxidase; GR: Glutathione Reductase; LPO: Lipid Peroxidation; Lipofuscin (LIF); ROS: Reactive Oxygen Species; SOD: Superoxide Dismutase; PMS: Phenazinemethosulphate; NBT: Nitoblu Tetrazolium; YC: Young Control; YEx: Young Exper...

Both radiation and anthracycline antibiotics may produce reactive oxygen species to cause cytotoxicity, and it has been suggested that some cellular antioxidant enzymes may be important for resistance to these agents. The human breast adenocarcinoma cell line MCF-7WT has a low level of glutathione peroxidase (GPX) activity. We have transfected MCF-7WT cells with a plasmid that contains the cDNA...

introduction : recurrent aphthous stomatitis (ras) is a common disease with unknown etiology and no treatment. the purpose of this study is to assess the relationship between serum antioxidants level and clinical manifestation. change in antioxidant level can lead inflammatory reaction through oxidative stress. materials & methods : a total 50 patients were selected for this cross sectional stu...

introduction : pemphigus comprises a group of diseases characterized by cutaneous and mucosal blistering. pemphigus vulgaris (pv) is the most common and important variant. recent reports have revealed the relatively high incidence of pv in iran. the onset or aggravation of many human diseases is attributed to oxidative stress and it has been suggested as one of the several factors responsible f...