Although glutaraldehyde is known to be bactericidal in solution, its potential use to create novel antibacterial polymers suitable for use in healthcare environments has not been evaluated. Here, novel materials were prepared in which glutaraldehyde was either incorporated into polyurethane using a simple "swell-encapsulation-shrink" method (hereafter referred to as "glutaraldehyde-impregnated ...

BACKGROUND Biologic valved grafts are important in cardiac surgery, and although several types of graft are currently available, most commercial xenografts tend to cause early disfiguration due to intimal proliferation and calcification. We studied the graft failure patterns on non-fixed and glutaraldehyde-fixed pulmonary xenograft in vivo animal experiment. MATERIALS AND METHODS Pulmonary va...

Material balance studies of glutaraldehyde in a river water-sediment system demonstrate that glutaraldehyde preferred to remain in the water phase. Glutaraldehyde was metabolized rapidly under both aerobic and anaerobic conditions. The pseudo-first-order half-life of catabolism, based on the loss of glutaraldehyde from the water phase, was 10.6 h aerobically and 7.7 h anaerobically. In contrast...

The RNAs of brome mosaic (BMV), barley stripe mosaic (BSMV), and tobacco mosaic (TMV) viruses were inactivated by reaction with buffered glutaraldehyde. Glutaraldehyde did not fix 4% BMV-RNA, 20% t-RNA, 5% polyadenylic acid, or 5% adenosine monophosphate into water-insoluble precipitates, or gels, in distilled water or in low or high ionic strength buffers nor did it change their ultraviolet (U...

Partitioning in charge-sensitive dextran-poly(ethylene glycol) aqueous phase systems reveals that fixation with even small concentrations of glutaraldehyde (e.g., 0.1% w/v) changes the surface properties of cells. While fixation with larger concentrations of glutaraldehyde (i.e., 1.85%) increases erythrocyte partition ratios, the effect of lower glutaraldehyde concentrations on the partition ra...

In this work the effect of crosslinking the enzyme esperase (E.C. 3.4.21.62) and the proteins bovine serum albumin and casein with the bifunctional compound glutaraldehyde on molecular mass increase was studied. Two common techniques for measuring molecular mass of proteins were used: SEC and SDS-PAGE. These techniques revealed that the proteins bovine albumin and casein, when subjected to chem...

Glutaraldehyde is used in pediatric dentistry as an alternative to formocresol in the treatment of primary teeth with diseased pulpal tissue. Because of concerns about the effects of glutaraldehyde in biological systems, the metabolism of ’4C (1, 5) glutaraldehyde (2.28 mC/mmole) in rat tissues investigated. Tissue slices prepared from liver, heart, kidney, and muscle were incubated in Krebs-Ri...

Alprazolam is most commonly used benzodiazepine in overdose for deliberate self-poisoning. Glutaraldehyde cold sterilization of medical, surgical and dental equipment. Poisoning due to accidental exposure as well self-poisoning common with glutaraldehyde. Self-inflicted or hesitational cuts are associated suicide attempted suicidal gestures their examination an important task forensic expert.