نتایج جستجو برای: glucoraphanin
تعداد نتایج: 158 فیلتر نتایج به سال:
Introduction Intake of broccoli sprouts, a rich source of the glucosinolate glucoraphanin, has been associated with decreased incidence, multiplicity, and tumor growth in animal cancer models.1-3 In 1992, Paul Talalay, MD, and colleagues at Johns Hopkins University identified the isothiocyanate, sulforaphane, a biologically active metabolite of glucoraphanin, as the compound in broccoli respons...
Chemoprotective or genotoxic effects of glucosinolates occurring in Brassica vegetables are attributed to their hydrolysis products formed upon tissue damage by plant myrosinase. Since Brassica vegetables, in which myrosinase has been heat-inactivated, still display bioactivity, glucosinolate activation has been attributed to intestinal bacteria. The aim of this study was to investigate whether...
Glucosinolates (GLSs) from a variety of Brassica oleracea, known locally as "mugnolo" and widely distributed in southern Italy, were studied. It was found that "mugnolo" inflorescences are characterized by the presence of the aliphatic GLSs glucoraphanin (1.79 µmol/g), glucoiberin, glucoerucin, and sinigrin, of the aromatic GLSs glucobarberin (0.56 µmol/g) and gluconasturtin, and of the indole ...
Organic agriculture requires cultivars that can adapt to organic crop management systems without the use of synthetic pesticides as well as genotypes with improved nutritional value. The aim of this study encompassing 16 experiments was to compare 23 broccoli cultivars for the content of phytochemicals associated with health promotion grown under organic and conventional management in spring an...
One of several challenges in design of clinical chemoprevention trials is the selection of the dose, formulation, and dose schedule of the intervention agent. Therefore, a cross-over clinical trial was undertaken to compare the bioavailability and tolerability of sulforaphane from two of broccoli sprout-derived beverages: one glucoraphanin-rich (GRR) and the other sulforaphane-rich (SFR). Sulfo...
In order to study the effects of nitrogen (N), phosphorus (P) and potassium (K) on the yield, the appearance eligibility ratio and the contents of total glucosinolates and glucoraphanin of cauliflower, the 311-A optimization regression design was used to conduct field experiments of N, P, K fertilizer treatments using winter cauliflower variety ‘‘HB16’’. The models of the balanced application f...
Broccoli (Brassica oleracea L. var. italica) is a globally popular vegetable because of its nutrient richness, especially glucosinolates (GSLs). The content GSLs in different organs broccoli varies greatly. However, few studies have focused on the differences biosynthesis-related genes organs. In this study, we selected extreme individuals from an F2 population and mixed them to form low high g...
The myrosinase enzyme hydrolyzes glucosinolates, among which is glucoraphanin, the precursor of anticancer isothiocyanate sulforaphane (SFN). main source glucoraphanin Brassicaceae; however, its natural concentration relatively low, limiting availability SFN. An option to obtain SFN exogenous production, through enzymatic processes and under controlled conditions, allowing complete conversion W...
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