نتایج جستجو برای: glucolized hemoglobin combination

تعداد نتایج: 434085  

Journal: :Therapeutics and clinical risk management 2016
Molly G Minze Lisa M Chastain

The global burden of type 2 diabetes is estimated to currently affect over 350 million people worldwide and is anticipated to continue increasing over the next 20 years. Current treatment guidelines recommend the choice of pharmacotherapy based upon patient-specific parameters, with combination therapy for patients with a hemoglobin A1c level ≥9%. A new combination therapy of insulin degludec +...

2012
Diewertje Sluik Heiner Boeing Jukka Montonen Rudolf Kaaks Annekatrin Lukanova Annelli Sandbaek Kim Overvad Larraitz Arriola Eva Ardanaz Calogero Saieva Sara Grioni Rosario Tumino Carlotta Sacerdote Amalia Mattiello Annemieke M. W. Spijkerman Daphne L. van der A Joline W. J. Beulens Susan van Dieren Peter M. Nilsson Leif C. Groop Paul W. Franks Olov Rolandsson Bas Bueno-de-Mesquita Ute Nöthlings

INTRODUCTION Observational studies have shown that glycated haemoglobin (HbA(1c)) is related to mortality, but the shape of the association is less clear. Furthermore, disease duration and medication may modify this association. This observational study explored the association between HbA(1c) measured in stored erythrocytes and mortality. Secondly, it was assessed whether disease duration and ...

Journal: :Blood 1992
F H Bosch J M Werre B Roerdinkholder-Stoelwinder T H Huls F L Willekens M R Halie

Red blood cell (RBC) fractions were studied after separation of whole blood by means of counterflow centrifugation, Percoll column (Pharmacia, Uppsala, Sweden), and a combination of both separation techniques. Mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular hemoglobin (MCH), and hemoglobin A1c (HbA1c) were measured in each fraction. From the res...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1972
J Bonaventura C Bonaventura B Giardina E Antonini M Brunori J Wyman

In the absence of organic phosphates human hemoglobin A digested with carboxypeptidase A (des His, Tyr beta) has high ligand affinity, a greatly reduced Bohr effect, and no heme-heme interaction. Under these conditions, it shows the simple, homogeneous ligand-binding kinetics characteristic of noncooperative heme proteins in which the high combination velocity for both O(2) and CO accounts, to ...

Journal: :Blood 1954
W W ZUELZER E KAPLAN

IN PREVIOUS CO? -IMUNICATIONS’-3 the hematologic effects of the gene for an abnormal hemoglobin, since designated as hemoglobin C, were described in two combinations: A-C, an asymptomatic carrier state in which the hemoglobin consists of a mixture of A (normal adult type) hemoglobin amid C; secondly S-C, a variant of sickle cell disease in which sickle hemoglobin S is produced together with hem...

Journal: :hepatitis monthly 0
sheng-hung chen institute of clinical medical science, school of medicine, china medical university, taichung, taiwan; school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan cheng-yuan peng school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, china medical university, taiwan. tel: +88-6422052121 hsueh-chou lai institute of clinical medical science, school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan; college of chinese medicine, china medical university, taichung, taiwan wen-pang su division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan chia-hsin lin division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan yu-fen li institute of biostatistics, china medical university, taichung, taiwan

conclusions in patients with chc g1 and receiving combination therapy, itpa snp-based index was an accurate and practical solution for prediction of severe anemia. background single-nucleotide polymorphisms (snp) in the inosine triphosphate pyrophosphatase (itpa) gene correlate with ribavirin (rbv)-induced anemia in patients with chronic hepatitis c (chc) receiving combination therapy. managing...

Journal: :Journal of bacteriology 1968
G H Bornside P J Bouis I Cohn

Intraperitoneal injection into mice of approximately 8 x 10(6) washed cells of Escherichia coli suspended in a lysate of washed human red blood cells or an aqueous solution of crystalline hemoglobin was lethal. E. coli suspended in washed intact erythrocytes, whole blood, plasma, or saline was innocuous. Fractionation of non-hemoglobin proteins from hemoglobin in lysates showed that only hemogl...

Journal: :The Journal of clinical investigation 1953
H M RANNEY D L LARSON G H McCORMACK

Recent observations (1, 2) in certain American Negroes, of a previously unrecognized abnormal hemoglobin, now designated as hemoglobin C,2 constitute a significant advance in knowledge of familial anemias. The introduction of filter paper electrophoresis (3, 4) for identification of abnormal hemoglobins (5, 6) has facilitated the study of specimens of hemoglobin from a large number of subjects....

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