Variations in the balance between cell proliferation and apoptosis could contribute to the etiology of gingival overgrowth. The aim of this study was to test the hypothesis that, in fibrotic gingival lesions, fibroblast proliferation is stimulated and apoptosis is decreased. Apoptotic index, caspase 3 expression, the proliferative index, FOXO1 expression, and histological inflammation were meas...

OBJECTIVE To compare the therapeutic effects of the application of doxycycline-full dose (100 mg) and sub-dose (20 mg) in the treatment of periodontal disease. MATERIAL AND METHODS A total of 60 patients with periodontal disease were examined. Patients are divided into two groups: A) treated with antimicrobial dose of 100 mg doxycycline once daily for 30 days, and B) treated with 2 x 20 mg/da...

The aim of the study was to evaluate the efficacy of Parodontax® (GlaxoSmith-Kline, Bühl, Germany) on the signs gingival inflammation and the enzyme activity of matrix metalloproteinase-8 (aMMP-8) in the gingival crevicular fluid. After approval by the ethics commission, a total of 50 volunteers participated in the study; group 1 (n = 25, age: 43 ± 12 years) with moderate gingivitis (BOP +) and...

Background A split-mouth longitudinal study was designed here to evaluate the effect of ozonated water delivered subgingivally through a jet device (Kent Ozone dental TY 820 jet) in controlling gingival inflammation of patients undergoing fixed orthodontic therapy. Materials and Methods Twenty-eight patients undergoing fixed orthodontic treatment following thorough oral prophylaxis were recal...

Gingival recession is commonly associated with plaque‐induced inflammation and calculus. A high frenal attachment is more important in gingival recession in the child‐patient. A healthy child‐patient with impeccable oral hygiene presented with localized gingival recession without plaque‐induced inflammation which led to the exploration of other possible etiologies. Multiple factors appeared to ...

Gingival recession is commonly associated with plaque-induced inflammation and calculus. A high frenal attachment is more important in gingival recession in the child-patient. A healthy child-patient with impeccable oral hygiene presented with localized gingival recession without plaque-induced inflammation which led to the exploration of other possible etiologies. Multiple factors appeared to ...

INTRODUCTION Gingival margin position in relation to synthetic crowns and crown length could be etiological factors in gingival health. CASE PRESENTATION A 27-year-old male presented with necrotizing ulcerative gingivitis with short clinical crowns suggestive of altered passive eruption. Three years after the initial diagnosis, he presented with crowns on the maxillary incisors. There were sh...

periodontal inflammation is associated with morphological changes in the blood vessels which may influence the regulation of gingival blood flow (gbf). our aim was to adapt the heat provocation test to the human gingiva to assess vascular reactivity in periodontal inflammation. method: gbf was recorded by laser doppler flowmetry before and after heat provocation in healthy volunteers (n = 50). ...

Introduction. Dental plaque is a major cause of gingival inflammation, which is, if not treated, transformed to periodontal disease. So, prevention and medication of gingival inflammation is focused on dental plaque control. Therefore, many professional pastes, gels or solutions are available at the market. We aimed to investigate the effectiveness of Gengigel® gel (Ricerfarma, Milano) in the t...

The purpose of this study was to evaluate the inflammatory response in dento-gingival units with or without attached gingiva in monkeys. Two different types of dento-gingival units with or without attached gingiva were established in premolar and first molar areas of three monkeys. In the experimental group, a part of the keratinized gingiva was removed with periodontal scissors following mucop...