Gestational trophoblastic disease (GTD) is characterized by abnormal proliferation of pregnancy-associated trophoblastic tissue with malignant potential. GTD covers a spectrum of tumors and tumor-like conditions and may occur in a benign form as hydatiform mole or as malignancy in the form of invasive mole or choriocarcinoma. GTD has become a curable malignant disease since the introduction of ...

Choriocarcinoma is a curable malignancy that occurred approximately 50% after term pregnancies, and prognosis in this form of gestational trophoblastic Disease (GTD) is Poor. The earliest onset choriocarcinoma after term pregnancy in one study was reported 3 weeks after delivery, but in current study, choriocarcinoma was diagnosed 2 weeks after delivery. 28 years-old women gravidity 2, parity 2...

Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma, placental-site ...

The World Health Organisation’s (WHO) classification of gestational trophoblastic disease includes complete, partial, invasive and metastatic hydatidiform mole, exaggerated placental site nodule or plaque and two malignant tumoursplacental site trophoblastic tumour and choriocarcinoma [1]. The incidence of gestational trophoblastic disease (GTD) in Sri Lanka according to a hospital based study ...

background: gestational trophoblastic disease (gtd) defines a heterogenenous group of interrelated lesions that arise from the trophoblastic epithelium of the placenta. there are several histologically distinct types of gtd: hydatiform mole (complete or partial), persistant/invasive gestational trophoblastic neoplasia (gtn), choriocarcinoma and placenta site trophoblastic tumors. the aim of thi...

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...

Gestational Trophoblastic Disease (GTD) in Latin America (LA) has a wide range of presentation and management, depending on socioeconomic, political and geographic variables [1,2,3]. Thus, while some referral centers have sophisticated methods for an early and accurate diagnosis and treatment, still there are a high number of patients admitted with a late Hydatidiform Mole (HM) or advanced Gest...

Gestational trophoblastic disease (GTD) is a condition of uncertain etiology, choriocarcioma, or placental-site hydatidiform moles, invasive moles, choriocarcinoma, and placental-site trophoblastic tumors. It arises from the abnormal proliferation of trophoblastic tissue and spreads beyond the uterus hematogenously. The early diagnosis of GTD is important to ensure timely and successful managem...

Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of

Gestational trophoblastic diseases (GTD) are a group of pregnancy-related disorders representing rare human tumours. They encompass premalignant disorders including complete (CHM), partial hydatidiform mole (PHM), exaggerated placental site (EPS), and placental-site nodule (PSN) as well as malignant disorders (also known as “gestational trophoblastic neoplasia [GTN]”) including invasive mole, c...