The killing of bacterial cells by chemical agents may be considered as the resultant of a reaction between two systems, the cells and their suspending medium and the germicide and its solvent. The method for testing sanitizing agents proposed by Weber and Black (1948) allows evaluation, on the basis of the two systems, of factors such as ions present in the suspending or diluting medium, organi...

Haematologica vol. 84(11):November 1999 nation of blood products. In this case, the transmission of a strain of P. rettgeri originated from the same donor, resulted in the death of two patients. Although Gram negative bacilli have been described as contaminants of blood products, we have not found any references concerning P. rettgeri.2,3 In the present case, the donor could not be studied, but...

Two years ago I brought before this Society what I thought to be strong arguments in favour of the substitution of cotton wool impregnated with a non-volatile antiseptic for the carbolic gauze commonly in use in the treatment of recent wounds. A year ago I related also to this Society a series of experiments which led me to believe that the spray of carbolic acid was useful only in so far as it...

The inactivation of virus-contaminated nonporous inanimate surfaces was investigated using adenovirus type 8, a common cause of epidemic keratoconjunctivitis. A 10-microl inoculum of adenovirus was placed onto each stainless steel disk (1-cm diameter), and the inoculum was allowed to air dry for 40 min. Twenty-one different germicides (including disinfectants and antiseptics) were selected for ...

The in vitro effectiveness of three germicides and three chemotherapeutic drugs against hospital-isolated strains of Pseudomonas aeruginosa was determined. Solutions of 1% acetic acid, 0.5% Amphyll, and 0.1% Betadine were bactericidal for six strains tested within 15 min at room temperature. Over a 3-year period at the Albany Medical Center Hospital, the percentages of strains of P. aeruginosa ...

Quaternary ammonium compounds, effective as sanitizing agents for food plant equipment under certain conditions, are not well suited as sanitizers for water of high mineral content. Mueller and Seeley (1951) have demonstrated under controlled conditions that various metallic cations can decrease the germicidal action of a quaternary in solution. Knowledge of how such interference takes place co...