aim : the purpose of this study was to compare the distribution of interleukin (il)-28b genotypes between iranian healthy individuals and patients with chronic hepatitis c based on the genotype. background : polymorphisms in the region of il-28b gene have been identified as the strongest genetic pretreatment predictor of sustained virological response (svr) in hepatitis c infection. patients an...

Objective(s) Matrix metalloproteinases comprise a family of enzyme that is able to degrade components of extra cellular matrix. There are single nucleotide polymorphisms in the promoter regions of several genes with ability to influence cancer susceptibility. The aim of this study was to analyses association between MMP2 and MMP9 promoter polymorphisms and head and neck squamous cell carcinoma...

â  â  background hepatitis c virus (hcv) infection is responsible for considerable morbidity and mortality worldwide. the hcv genotype has a geographic distribution and an important role in clinical and histological outcomes. this study determined hcv genotypes and their related risk factors among patients from khuzestan province, southwest iran. methods in a cross-sectional study, 223 patients...

aim and objectives: the hepatitis c virus (hcv) is essentially hepatotropic but virus compartment have also been found in other important extra hepatic sites. detection of hcv rna in extra hepatic reservoirs such as peripheral blood mononuclear cells (pbmcs) is important for determining of disease progression and effective treatment. the present study aimed to determining of different hcv genot...

results the predominant genotype among bahraini patients was type 1 (36.71%), followed by genotypes 3 and 4 (15.6% each) and the lowest frequency was found for genotype 2 (3.9%). among genotype 1, subtype 1b had the highest frequency (21.09%), followed by subtype 1a (14.06%). among genotype 3, subtype 3a had the highest frequency (11.72%), while among genotype 4, most of subtypes were undetermi...