نتایج جستجو برای: genomic linkage
تعداد نتایج: 165247 فیلتر نتایج به سال:
Genomic selection is a promising challenge for discovering genetic variants influencing quantitative and threshold traits for improving the genetic gain and accuracy of genomic prediction in animal breeding. Since a proportion of genotypes are generally uncalled, therefore, prediction of genomic accuracy requires imputation of missing genotypes. The objectives of this study were (1) to quantify...
جنس کلئوم متعلق به خانواده کور (capparaceae) می باشد. در بررسی این جنس در خراسان 7 گونه یافت شده است . تاکساهای مذکور به منظور تعیین ویژگیهای تشریحی مورد مطالعه قرار گرفتند. هدف دیگر این پژوهش مطالعه جنس کلئوم با استفاده از روش تاکسونومی عددی می باشد. داده ها (ویژگیهای تشریحی) توسط سه روش تجزیه ای خوشه ای complete linkage, single linkage, average linkage آنالیز شدند. نتایج این بررسی مطالعات تاک...
introduction: genomic selection refers to selection decisions based on genomic breeding values (gebv). the gebv are calculated as the sum of the effects of dense genetic markers across the entire genome, thereby potentially capturing all the quantitative trait loci (qtl) that contribute to variation in a trait. the qtl effects, inferred from markers, are first estimated in a large reference pop...
The Mexican tetra, Astyanax mexicanus, is a unique model system consisting of cave-adapted and surface-dwelling morphotypes that diverged >1 million years (My) ago. This remarkable natural experiment has enabled powerful genetic analyses of cave adaptation. Here, we describe the application of next-generation sequencing technology to the creation of a high-density linkage map. Our map comprises...
Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gat...
the aim followed in this study was to use the multi and single trait analyses for a prediction of genomic and traditional breeding values and to make a comparison of the accuracies of these methods. a base population of 100 animals (50 males and 50 females) was randomly mated for 50 generations to create linkage disequilibrium among loci. the simulated genome size was 10 morgan, equally divided...
ObjectivesWe aimed to evaluate the concordance between epidemiologically determined transmission and genetic linkage of Klebsiella pneumoniae carbapenemase (KPC)-producing (KPC-Kp).MethodsWe included consecutive KPC-Kp carriers December 2016 April 2017 in a hospital endemic for KPC-Kp. We assessed epidemiological relatedness patients by prospective investigations infection control team. The pro...
Current efforts to find disease-causing genes depend on patterns of linkage disequilibrium in human populations. Recent work has shown that linkage disequilibrium can extend over much larger genomic regions than expected, and that the patterns of linkage disequilibrium can differ markedly among populations.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic nephropathy, which is characterized by replacement of renal parenchyma with multiple cysts. In Iran, the disease prevalence within the chronic hemodialysis patient population is approximately 8-10%. So far, three genetic loci have been identified to be responsible for ADPKD. Little information is available concernin...
Comprehensive genome scans involving many thousands of SNP assays will require significant amounts of genomic DNA from each sample. We report two successful methods for amplifying whole-genomic DNA prior to SNP analysis, multiple displacement amplification, and OmniPlex technology. We determined the coverage of amplification by analyzing a SNP linkage marker set that contained 2320 SNP markers ...
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