نتایج جستجو برای: genome
تعداد نتایج: 229243 فیلتر نتایج به سال:
it is now universally accepted that dna is the main target for damages caused by physical and chemical genotoxicants. although there are different methods to measure directly the induced dna damages but due to fast repair processes in cellular environment, most of the damages would be repaired even before sampling, therefore processed dna damages, i.e. damages left unrepaired after acting repai...
myocardial infarction (mi) and its major determinant, coronary artery disease (cad), are complex diseases arising from the interaction between several genetic and environmental factors. until recently, the genetic basis of these diseases was poorly understood. genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases...
the archaeological evidence suggests that iran has been one of the first origins of sheep domestication in the world. this study aims to investigate the genetic diversity of indigenous iranian sheep breeds using mitochondrial dna (mtdna) and to explore the evolutionary history of sheep domestication in iran. single nucleotide polymorphism (snp) markers in the control region of mtdna were used t...
background although certain hbv mutations are known to affect the expression of hepatitis e antigen, their association with hbv viral level or clinical outcomes is less clear. objectives we evaluated associations between different mutations in the basal core promoter (bcp) and pre-core (pc) regions of hbv genome and subsequent changes in hbv viral dna level over seven years in a population of u...
Background: White spot syndrome virus (wssv) is the causing agent for white spot disease in shrimp and many crustaceans. This disease is highly contagious and can cause death within 3–10 days under normal culture conditions. Therefore, early diagnosis of the virus is a necessity. Materials and Methods: Primers were designed for three regions of the virus genome and one region of the shrimp geno...
conclusions fulminant hepatitis b is associated with distinct mutational patterns of hbv, underlining that genomic diversity of the virus is an important factor determining its pathogenicity. results the most commonly detected diversities affect regulatory motifs of hbv in the core and s region, indicating that these alterations may convert the virus to an aggressive strain. moreover, mutations...
تعداد محدودی مارکرهای ریزماهوارک مناسب برای بررسی تنوع وراثتی گونه ی h. bulbosumوجود دارد. در این مطالعه قابلیت انتقال ریزماهوارک های جو زراعی به گونه ی h. bulbosumو تنوع پذیری آنها مورد بررسی قرار گرفته است. از 93 زوج پرایمر ssr آزمایش شده همگی در گونه ی h. vulgare(11 نمونه بذر) قطعاتی از dna را تکثیر نمودند ولی تنها 46 زوج از آنها (61/51%) قابلیت انتقال به گونه h. bulbosum (5 نمونه بذر) با سط...
شمارش کروموزومی و تجزیه کاریوتیپ تعداد پنج مانگرو تک لپه از در دارما و ساحل پارادیپ در اوریسا (هندوستان) نشان داد که در گونه 48=n2 porteresia coarctata ، در گونه های crinum defixum و 22=n2 cryptocaryne ciliata ، در گونه های asparagus racemosus var. javanica و cyperus cephalotes 20=n2 می باشد. طول کل کروموزومی از 44/42 در گونه asparagus racemosus var. javanica تا 86/93 در گونه crinum defixum ...
the genome of iranian wheat stripe virus (iwsv), a tentative member of the genus tenuivirus, is comprised of three ambisense and one negative sense rna segments. the coat and non-structural proteins encoded by the vcrna3 and vrna4 genes, respectively, were efficiently translated in vitro. translated proteins of vcrna3 and vrna4 transcripts were approximately 35000 and 22000 in mr, respectively,...
background there are hoarding documents for the biological importance of cyclooxygenase-2 (cox-2) in pancreatic carcinogenesis. we aimed to thoroughly investigate the dna sequence variations of whole cox-2 exons in a large case-control study of pancreatic cancer by direct sequencing. methods the entire exonic regions of cox-2 including 10 exons were sequenced in the germline dna of 96 patient...
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