OBJECTIVE To study the relations between maternal occupational exposure to solvents during pregnancy and the risk of congenital malformations. METHODS A prospective population-based cohort, specifically designed to study the impact of maternal exposure to solvents on the risk of congenital malformations, began in 2002 in three districts of Brittany (France). 3421 pregnant women were recruited...

Thirteen cases of congenital malformations of uterus were discovered during past ten years at Abbasi Shaheed Hospital, KMC, Karachi. They varied from uterus dideiphys to uterus unicornis. Similar malformations presented different clinical pictures in different individuals. However, most of the congenital malformations encountered did not interfere with fertility and eight cases had conceived wi...

INTRODUCTION Tuberculosis is a chronic infectious disease, and the morbidity associated with it has major health implications. When tuberculosis affects the genital organs of young females, it has the devastating effect of causing irreversible damage to their fallopian tubes, resulting in a possible tubercular pyosalpinx and infertility. However, the disease often remains silent or presents wit...

Abstract Introduction Genital malformations are a common clinical occurrence that can be represented using different classifications. Reproducibility is an essential quality characteristic for classification, and it plays important role, especially in consultations the treatment of infertile patients obstetric management. The aim this study to demonstrate reproducibility practicality three comm...

Introduction. The data on psychological status of patients with congenital defects of urogenital tract are very scarce, yet it was confi rmed that reactions to the information about diagnosed anomaly and then patients’ attitudes toward treatment vary with a kind of malformation, patient’s age and personality. Aim of the study. The aim of the study was to analyze the correlation between the seve...

A 7 year old boy with minor facial anomalies, the Rieger eye malformation, reduced vision, genital anomalies, and severe mental retardation had deletion of the segment 4q24-->q26. His phenotypically normal father had a balanced insertion of that segment into the distal long arm of chromosome 6: 46,XY,ins(6;4)(q26;q24q26). Microsatellite loci flanking the RIEG gene on 4q25 were deleted giving in...

Abstract Background Classic bladder exstrophy is a complex, multi-system congenital malformation affecting formation of the genitourinary system, pelvis, and abdominal wall. Main body Historically children with this abnormality were consigned to poor outcomes quality life. Modern advancements in diagnosis management disorder have resulted low mortality rates shifted clinical focus toward optimi...