نتایج جستجو برای: genetically significant dose

تعداد نتایج: 1511435  

2014
Rigmor Thorstensson Birger Trollfors Nabil Al-Tawil Maja Jahnmatz Jakob Bergström Margaretha Ljungman Anna Törner Lena Wehlin Annie Van Broekhoven Fons Bosman Anne-Sophie Debrie Nathalie Mielcarek Camille Locht

BACKGROUND Acellular pertussis vaccines do not control pertussis. A new approach to offer protection to infants is necessary. BPZE1, a genetically modified Bordetella pertussis strain, was developed as a live attenuated nasal pertussis vaccine by genetically eliminating or detoxifying 3 toxins. METHODS We performed a double-blind, placebo-controlled, dose-escalating study of BPZE1 given intra...

Journal: :Toxicology and applied pharmacology 2004
S Havarinasab L Lambertsson J Qvarnström P Hultman

The organic compound ethylmercurithiosalicylate (thimerosal), which is primarily present in the tissues as ethylmercury, has caused illness and several deaths due to erroneous handling when used as a disinfectant or as a preservative in medical preparations. Lately, possible health effects of thimerosal in childhood vaccines have been much discussed. Thimerosal is a well-known sensitizing agent...

ژورنال: طلوع بهداشت یزد 2019

Introduction: Genetically modified plants species of plants are produced by the genetic engineering of agricultural science and the addition of specific genes in their genetic sequences with the aim of optimizing the product and creating desirable traits. This study examined the remains of Cry1A(b) and P35 genes in blood of rats fed with genetically modified rice. Methods: This study was exper...

2010
A. Lievens G. Bellocchi D. De Bernardi W. Moens C. Savini M. Mazzara G. Van den Eede M. Van den Bulcke

Owing to the labelling requirements of food and feed products containing materials derived from genetically modified organisms, quantitative detection methods have to be developed for this purpose, including the necessary certified reference materials and calibrator standards. To date, for most genetically modified organisms authorized in the European Union, certified reference materials derive...

Journal: :International Journal of Radiation Oncology*Biology*Physics 2015

ژورنال: حقوق پزشکی 2011
آل بویه, محمود, ربیعی, مریم, رستگار, حسین, مهدی‌زاده, مهرانگیز,

Since 1990s genetically modified foods began to appear in the market place. The most common genetically modified products are soy bean, corn, cotton and canola and the most important genetically modified characteristics are herbicide tolerance and insect resistance. Worries about safety of genetically modified foods led to establishment of labeling rules. Since 1997 based on regulations of Euro...

Journal: :iranian journal of biotechnology 2014
ali motevallizadeh ardekani

in recent years, biotechnology has provided the possibility of creating genetically modified (gm) organisms by transferring genes from sources such as viruses, bacteria, animals, and plants into usually unrelated species. this ability to overcome insurmountable physiological barriers by exchanging genetic materials among all living organisms is a double-edged sword. on the one hand, it allows t...

Journal: :Teratology 1991
F G Biddle L R Mulholland B A Eales

The WB/ReJ and C57BL/6J strains were compared in their time and dose responses to acetazolamide administered in a single subcutaneous injection regime. WB/ReJ has a genetically determined, high-frequency, transient fetal edema that has maximum expression on day 14 and is resolved by day 18. Acetazolamide, at 1,000 mg/kg, appears to induce edema in WB/ReJ with a time of response on days 9 and 10...

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