نتایج جستجو برای: genetic background

تعداد نتایج: 1398542  

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2003

Journal: :Epigenomics 2013
Jerome D Boyd-Kirkup Christopher D Green Gang Wu Dan Wang Jing-Dong J Han

It is tempting to assume that a gradual accumulation of damage 'causes' an organism to age, but other biological processes present during the lifespan, whether 'programmed' or 'hijacked', could control the type and speed of aging. Theories of aging have classically focused on changes at the genomic level; however, individuals with similar genetic backgrounds can age very differently. Epigenetic...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1973
T P Webster

In some populations of the salamander Plethodon cinereus, two polymorphic esterase loci are in linkage disequilibrium. Short-term stability of the linkage disequilibrium is demonstrated by an age class analysis. Long, perhaps very long, term stability is suggested by its distribution. This stability and concordant geographic variation in allelic frequencies imply selective origin and maintenanc...

Journal: :Journal of clinical microbiology 2007
Patrice Francois Manuela Bento Gesuele Renzi Stephan Harbarth Didier Pittet Jacques Schrenzel

One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the ri...

Journal: :Journal of Antimicrobial Chemotherapy 2008
Christof von Eiff Dominik Maas Gunnar Sander Alexander W. Friedrich Georg Peters Karsten Becker

OBJECTIVES Recently, a rapid screening tool for methicillin-resistant Staphylococcus aureus (MRSA) has been introduced that applies a novel detection technology allowing the rapid presence or absence of MRSA to be determined from an enrichment broth after only a few hours of incubation. To evaluate the reliability of this new assay to successfully detect MRSA strains of different origin and clo...

Journal: :Public health 2012
G A Zielhuis

Biobanks are a key resource in unravelling the association between genetic background, lifestyle and environmental determinants of the incidence, natural course and treatment response for various complex diseases and health traits. Biobanks are goldmines for epidemiological research, provided that they are set up properly, enable multicentre collaboration, and are available for use by all serio...

Journal: :Twin research and human genetics : the official journal of the International Society for Twin Studies 2008
Gonneke Willemsen Toos C E M van Beijsterveldt Caroline G C M van Baal Dirkje Postma Dorret I Boomsma

The present study assessed the prevalence of asthma and allergy, and estimated the importance of genetic and environmental influences on asthma and allergy liability and their association. Longitudinal data on self-reported, doctor-diagnosed asthma and allergy were collected in over 14,000 individuals registered with the Netherlands Twin Register. Structural equation modeling was used for univa...

Journal: :Reproductive BioMedicine Online 2007

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