نتایج جستجو برای: gene optimization

تعداد نتایج: 1450764  

Journal: :Critical Reviews in Biochemistry and Molecular Biology 2012

Journal: :nanomedicine journal 0
roya cheraghi department of nanobiotechnology, faculty of biological sciences, tarbiat modares university, tehran, iranسازمان اصلی تایید شده: دانشگاه تربیت مدرس (tarbiat modares university) mohsen alipour department of nanobiotechnology, faculty of biological sciences, tarbiat modares university, tehran, iranسازمان اصلی تایید شده: دانشگاه تربیت مدرس (tarbiat modares university) mahboobeh nazari monoclonal antibody research center, avicenna research institute, acecr, tehran, iran saman hosseinkhani department of biochemistry, faculty of biological sciences, tarbiat modares university, tehran, iranسازمان اصلی تایید شده: دانشگاه تربیت مدرس (tarbiat modares university)

objective(s): pei based nanoparticle (np) due to dual capabilities of proton sponge and dna binding is known as powerful tool for nucleic acid delivery to cells. however, serious cytotoxicity and complicated conditions, which govern nps properties and its interactions with cells practically, hindered achievement to high transfection efficiency. here, we have tried to optimize the properties of ...

Journal: Nanomedicine Journal 2017
Mahboobeh Nazari, Mohsen Alipour, Roya Cheraghi Saman Hosseinkhani

Objective(s): PEI based nanoparticle (NP) due to dual capabilities of proton sponge and DNA binding is known as powerful tool for nucleic acid delivery to cells. However, serious cytotoxicity and complicated conditions, which govern NPs properties and its interactions with cells practically, hindered achievement to high transfection efficiency. Here, we have tried to optimize the properties of ...

Bovine chymosin enzyme is one of the most commonly used enzymes in the dairy industry. The production of this enzyme from its natural source does not meet the needs of this huge industry. The production of recombinant bovine chymosin in plants can be a good alternative to native enzyme. Insertion and expression of foreign genes in plants can occur in the nucleus and chloroplast organelles. The ...

Journal: :research in pharmaceutical sciences 0
h mir mohammad sadeghi m rabbani s fazeli

alkaline phosphatase is an enzyme with widespread use in research and industry such as protein labeling, dephosphorylation of nucleic acids, and enzyme based biosensors. in the present study, alkaline phosphatase gene was inserted into the pet15b vector. the recombinant dna was then expressed using iptg as an inducer. the expression of this enzyme was optimized by changing expression conditions...

Ali Hatef Salmanian Amir Mousavi Faranak Hadi Kambiz Akbari Noghabi

The engineering of transgenic canola (Brassica napus L. ) to make tolerance to the broad-spectrum herbicide, glyphosate, is one of the most effective approaches for weed management. Glyphosate inhibits the enzyme EPSPS (5-enolpyruvylshikimate-3-phosphate synthase) enzyme which functions in the shikimate pathway and has a key role in biosynthesis of aromatic amino acids required for survival of ...

Esmaeili , Aghil, Ghofrani, Mahdi, Honari, Hossein, Safaei, Sadegh,

Background & Objective: In order to enhance the expression of soluble proteins and facilitate their purification and development of multi-functional polypeptide , chimerical recombinant proteins have been invented . The purpose of this study was to construct ctxB-gfp-stxB gene cassette to measure the uptake and excretion of chimerical antigen in future studies.   Materials & Methods: After prep...

Journal: :iranian biomedical journal 0
حامد لشکریان hamed lashkarian جمشید راهب jamshid raheb کیانا شاه زمانی kiana shahzamani حسین شاهبانی hossein shahbani مهدی شمس آرا mehdi shamsara

background: cholesterol oxidase (cho) has various clinical and industrial applications. recently, microbial cho have received a great attention for their wide usage in medicine. here, taxonomic characterizations of isolated strain from soil, optimization of the conditions for cho production and biochemical characterizations of produced cho enzyme were described. finally, cho gene was cloned int...

Journal: :jundishapur journal of microbiology 0
abbas mohajeri tuberculosis and lung disease research center, tabriz university of medical sciences, tabriz, ir iran yones pilehvar-soltanahmadi tuberculosis and lung disease research center, tabriz university of medical sciences, tabriz, ir iran; department of medical biotechnology, faculty of advanced medical sciences, tabriz university of medical sciences, tabriz, ir iran jalal abdolalizadeh drug applied research center, tabriz university of medical sciences, tabriz, ir iran pouran karimi neurosciences research center (nsrc), tabriz university of medical sciences, tabriz, ir iran nosratollah zarghami tuberculosis and lung disease research center, tabriz university of medical sciences, tabriz, ir iran; department of medical biotechnology, faculty of advanced medical sciences, tabriz university of medical sciences, tabriz, ir iran; tuberculosis and lung disease research center, tabriz university of medical sciences, tabriz, ir iran. tel: +98-4113378093

conclusions the obtained results indicate that rsm is an effective method for the optimization of culture conditions for hes gene expression in e. coli. results a maximum rhes mrna level of 376.16% was obtained under the following conditions: 0.6 mm iptg, 7 hours post-induction time, and 0.9 cell density before induction. the level of rhes mrna was significantly correlated with post-induction t...

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