نتایج جستجو برای: gca

تعداد نتایج: 1655  

Journal: :Clinical and experimental rheumatology 2008
G S Breuer R Nesher G Nesher

OBJECTIVE Characterize patients with negative temporal artery biopsies in regard to their eventual diagnoses, and to find features that would differentiate biopsy-negative GCA from non-GCA patients. METHODS 58 patients with negative biopsies were included. Patients' data and final diagnoses were obtained from medical records. Biopsy-negative GCA was diagnosed when the American College of Rheu...

Journal: :The Israel Medical Association journal : IMAJ 2014
Gideon Nesher

Giant cell arteritis (GCA) is considered to be a T cell-dependent disease. Autoantibodies have not consistently been found in GCA. The exception is antiphospholipid antibodies (APLA), which were found in 30-80% of GCA cases. Recently, efforts have been made to seek autoantibodies in GCA using newer methods of detection: serological identification of antigens by recombinant cDNA expression cloni...

Journal: :Seminars in arthritis and rheumatism 2004
Miguel A Gonzalez-Gay

OBJECTIVES Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are common and frequently overlapping diseases. In this manuscript similarities and differences between these conditions have been assessed. METHODS A retrospective review of the literature was conducted. Reports emphasizing features in common and possible differences are reviewed. RESULTS GCA and PMR are characterized b...

Journal: :Clinical and experimental rheumatology 1999
V Petursdottir E Nordborg N Moraghebi M Persson C Nordborg

OBJECTIVE Giant cell arteritis (GCA) is a chronic form of vasculitis which predominantly affects women over 50 years of age. The aim of this study was to analyse the presence of estrogen receptor alpha (ER) in the temporal arteries of patients with GCA. METHODS Inflamed temporal artery biopsies from 43 GCA patients were stained with monoclonal antibodies to two different segments of the ER an...

2016
Mar Pujades-Rodriguez Bram Duyx Sara L Thomas Dimitris Stogiannis Liam Smeeth Harry Hemingway

OBJECTIVES Evidence of the association of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) with the full range of cardiovascular diseases (CVDs) is limited. We examined their relationship with the first clinical presentation of the 12 most common CVDs in an unselected population-based cohort of men and women. METHODS We analysed CArdiovascular disease research using LInked Bespoke ...

2018
Edsel B Ing Royce Ing Xinyang Liu Angela Zhang Nurhan Torun Michael Sey Christian Pagnoux

Purpose Giant cell arteritis (GCA) is the most common systemic vasculitis in the elderly and can cause irreversible blindness and aortitis. Varicella zoster (VZ), which is potentially preventable by vaccination, has been proposed as a possible immune trigger for GCA, but this is controversial. The incidence of GCA varies widely by country. If VZ virus contributes to the immunopathogenesis of GC...

2013
XIAO-SHAN FENG YU-FENG WANG SHU-GUANG HAO YI RU SHE-GAN GAO LI-DONG WANG

The aim of this study was to characterize histo-chemical patterns and Das-1 and Ki67 protein expression in gastric cardia adenocarcinoma (GCA) and intestinal metaplasia (IM) lesions adjacent to GCA. Histochemical techniques, including Alcian blue/periodic acid-Schiff (AB/PAS), high iron diamine/Alcian blue (HID/AB) and avidin-biotin-peroxidase complex (ABC) immunohistochemistry were applied to ...

Journal: :Annals of the rheumatic diseases 2010
Markus Aschwanden Friederike Kesten Martin Stern Christoph Thalhammer Ulrich A Walker Alan Tyndall Kurt A Jaeger Christoph Hess Thomas Daikeler

OBJECTIVE To define the specificity and extent of duplex sonography (DS) findings suggestive of vessel wall inflammation in patients with giant cell arteritis (GCA). METHODS Patients admitted between December 2006 and April 2009 to the University Hospital Basel with a suspicion of GCA were eligible for the study. DS of 2x11 arterial regions was performed in all study participants, and America...

2017
Lian-Qun Zhang Xin Song Xue-Ke Zhao Jia Huang Peng Zhang Lu-Wen Wang Hui Meng Jian-Wei Ku Guo-Qiang Kong Tao Jiang Xin-Min Li Xiao-Long Lv Teng Ma Guo Yuan Min-Jie Wu Shou-Jia Hu Shuang Lv Tang-Juan Zhang Ling-Fen Ji Zong-Min Fan Neng-Chao Wang Yao-Wen Zhang Fu-You Zhou Li-Dong Wang

OBJECTIVE : This study aimed to determine if gastric cardia adenocarcinoma (GCA) risk was associated with the lys (A or *2) allele at the rs671 (glu504lys) polymorphism within the aldehyde dehydrogenase 2 (ALDH2) gene in a Chinese Han population. We also aimed to investigateALDH2 genotypic distributions between subjects from high- and low-incidence areas for both GCA and esophageal squamous cel...

Journal: :Annals of the Rheumatic Diseases 2021

Background: Several clinical patterns of giant cell arteritis (GCA) have been described including cranial GCA (c-GCA), large vessel (LV-GCA), mixed forms c-GCA and LV-GCA (mixed-GCA), even polymyalgia rheumatica (PMR) that has associated with some degree subclinical vascular inflammation could be present in the patients. However, many questions about this disease its subtypes remain unanswered....

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