BACKGROUND To determine the diagnostic Accuracy of Focused Assessment Sonography for Trauma (FAST) and repeated FAST in the patients with blunt abdominal trauma. METHODS In this retrospective study we collected the data of all patients from September 2007 to July 2011 with gastrointestinal injury. The intraoperative outcome was compared with FAST technique and the repeated or delayed sonograp...

The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This study aimed to determine whether severe burns affect the gastrointestinal microbiome during the ear...

Background: Caustic substance ingestion is known for causing a wide array of gastrointestinal and systemic complications. In Russia, ingestion of acetic acid is a major problem which annually affects 11.2 per 100,000 individuals. The objective of this study was to report and analyze main complications and outcomes of patients with 70% concentrated acetic acid poisoning. Methods: This was a retr...

Gastrointestinal toxicity caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is the most frequent drug side effect in the United States. NSAIDs are implicated in the development of complicated peptic ulcer disease and injury to the small bowel and colon. NSAIDs interfere with prostaglandin-mediated epithelial defense mechanisms and also cause direct epithelial toxicity. Current and future ...

Upper gastrointestinal tract mucosa is prone to injury. Drugs may disturb gastric mucosa protective mechanisms and cause damage. Injury by NSAIDs is a well described complication. Nifedipine, a widely used drug, was not described before as having a potential to damage gastrointestinal mucosa. We describe here, two patients, who developed esophageal and gastric mucosal damage, probably related t...

The coronavirus disease-2019 (COVID-19) pandemic is a public health threat impacting people all over the world. Although severe acute respiratory syndrome (SARS-CoV-2) was identified as virus for system, it might be responsible digestive symptoms associated with COVID-19. Common gastrointestinal in COVID-19 patients are anorexia, vomiting, nausea, abdominal pain, and diarrhea, addition to abnor...

Childhood gastrointestinal dysfunction has been recognized as the triggering elements of multiple organ failure. The causes of gastrointestinal dysfunction include: injury of intestinal barrier, release of inflammatory mediators, translocation of intestinal bacteria, gastrointestinal mucosal ischemia and anoxia injury caused by abnormal intestinal blood flow perfusion, and apoptosis of gastroin...