aim : the aim of this study is to evaluate the polymorphism in bax gene and its association with some clinical pathology traits in gastric cancer.   background : gastric cancer is considered as the fourth most common cancer in the north and northwest of iran. bcl2 family has a key role in regulation of apoptosis, and any changes in the expression of bcl2 lead to cancer. patients and methods : b...

introduction: lymphomas as a group rank seventh as the most leading cause of death in cancers. stomach is the most common extra nodal site of primary lymphomas. on the other hand, new information demonstrates that malt lymphoma responds to helicobacter antibiotic therapy. we therefore decided to determine the frequency of distribution of helicobacter pylori infection in primary gastric lymphoma...

Chronic infection with the gastric bacterial pathogen Helicobacter pylori causes gastric adenocarcinoma in a particularly susceptible fraction of the infected population. The intestinal type of gastric cancer is preceded by a series of preneoplastic lesions that are of immunopathological origin, and that can be recapitulated by experimental infection of C57BL/6 mice with Helicobacter species. S...

lipomas are rare gastric tumors that comprise less than 1% of gastric tumors. these tumors are usually without clinical manifestations, but sometimes they may present with severe symptoms like bleeding,intussusception, or abdominal pain. in endoscopic assessment, they manifest with subm ucosal masses with intact epithelium. endosonography and ct scan can help in diagnosis. surgical resection of...

Helicobacter pylori transactivates the Epidermal Growth Factor Receptor (EGFR) and predisposes to gastric cancer development in humans and animal models. To examine the importance of EGFR signalling to gastric pathology, this study investigated whether treatment of Mongolian gerbils with a selective EGFR tyrosine kinase inhibitor, EKB-569, altered gastric pathology in chronic H. pylori infectio...

Gastric Ulceration in the Adult Gastric ulceration syndrome (GUS), a complicated and multi-factorial problem, is a common disorder of the stomach of mature horses. Horses that are turned out to pasture and are not involved in work have normal stomachs as do most horses used for light work or pleasure (Murray 1994). In recent years the widespread nature of this disorder has gained increased reco...

Gastric carcinoma (GC) is a biologically heterogeneous disease involving numerous genetic and epigenetic alterations. A very small proportion of GCs can be caused by a specific germ-line mutation of the E-cadherin gene (CDH1). Sporadic GC is developed through multistep processes that begin with Helicobacter pylori-induced atrophic gastritis. Epstein-Barr virus is another infectious cause of GC,...