.....................................................................................................................................7 INTRODUCTION ............................................................................................................................9 REVIEW OF THE LITERATURE................................................................................................10 ...

Tumor diameter or T stage does not reflect the actual tumor burden and is not able to estimate accurate prognosis of gastric cancer. The current study aimed to evaluate the prognostic value of tumor volume (V) for gastric cancer. A total of 3409 enrolled gastric cancer patients were randomly divided into training set (n = 1705) and validation set (n = 1704). Tumor volume was calculated by the f...

Gastric cancer accounts for approximately 8% of new cancers worldwide (Jemal et al., 2011). Early diagnosis and accurate preoperative staging are critical for improving outcomes, and this includes the identification of the tumor location, depth of invasion, lymph node status, and the presence of metastasis (Monig et al., 2002; Chen et al., 2007; Makino et al., 2011). Current methods for the det...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

Hexokinase 1 (HK1) and pyruvate kinase M2 (PKM2) are two key regulators in glycosis and oncogenic markers in cancers. In the present study, we investigated the expression profile by Western blotting and immunohistochemistry and determined their prognostic values in the gastric cancer. Expression of HK1 and PKM2 was remarkably increased in gastric cancer tissues and was significantly associated ...

Successful management of gastric cancer depends on early detection and accurate staging of disease as surgery is the only curative treatment method for localized disease. Endoscopic ultrasound has been the most reliable nonsurgical method in evaluation of the primary tumor, however, recent studies comparing the preoperative staging of gastric cancer by endoscopic ultrasound with multidetector C...

Multidetector CT (MDCT) gastrography has been regarded as a promising technique for the preoperative imaging of gastric cancer. It has the ability to produce various three-dimensional (3D) images. Because 3D reconstruction images are more effective and intuitive for recognizing abnormal changes in the gastric folds and subtle mucosal nodularity than two-dimensional images, 3D MDCT gastrography ...

The growing role of multimodal treatment plans for advanced gastric cancer has contributed to the development of more accurate preoperative staging strategies. The high diagnostic efficacy of video-laparoscopy as regards the M factor has been reported by many; preoperative laparoscopy therefore permits to avoid unhelpful surgical exploration in case of peritoneal dissemination of tumor or liver...

Objective: To investigate diagnostic value and clinical significance of ultrasonic contrast and endoscopic ultrasonography in preoperative staging of gastric carcinoma. Methods: 65 patients with gastric cancer were randomly selected from our hospital from February 2015 to February 2017 as the study objects and all of them were treated with ultrasonic contrast and endoscopic ultrasonography foll...

BACKGROUND The accuracy of endoscopic ultrasonography (EUS) for preoperative staging of gastric cancer varies. The aim of this study was to investigate the accuracy of EUS tumor (T) and node (N) staging, and to identify the histopathological factors influencing accuracy based on the detailed tumor depth of gastric cancer. METHODS In total, 309 patients with gastric cancer with confirmed patho...