background gastric cancer is the second most common cause of cancer death worldwide. lentinan was shown to induce apoptosis in gastric cancer cells and could be used for the treatment of gastric cancer. objectives in this study, we analyzed anticancer effect of lentinan, a fungal β-glucan, on the gastric adenocarcinoma cell line (ags). materials and methods we used the dna ladder and tunnel app...

It is well established that the esophageal distention (ED) leads to gastric relaxation, partly by vago-vagal reflex, but till now, the effect of ED on gastric acid secretion has not been investigated. The aim of this study was to investigate the effect of ED on basal and stimulated gastric acid secretion. Methods: Adult male Wistar rats (200-240 g) were deprived of food but not the water 24 h b...

Objective(s):MiRNAs have been proposed to be key regulators of tumorigenesis, progression and metastasis. However, their effect and prognostic value in gastric cancer is still poorly known. Materials and Methods: Gastric cancer cell lines were cultured. Tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time PCR (qRT-PCR) analysis. The tissue microarrays (T...

background: upper gastrointestinal (gi) bleeding remains a problem in critically ill-newborns. the use of h 2 blockers, by maintaining gastric ph ³ 4, reduces the risk of stress-ulceration and gastric hemorrhage. this study therefore, has evaluated the effects of short-term prophylactic‎ ranitidine in controlling gastric ph and prevention of gi bleeding in neonates.   methods: this randomized c...

objective(s):fumonisins are a group of toxic and carcinogenic mycotoxins, which contaminate the grains and their products. the aim of this study was to examine the apoptotic and proliferative activity of mouse gastric mucosa following administration of fumonisin b1 (fb1).    materials and methods: twenty-nine female mice divided into treatment (n=15) and control (n=14) groups. the treatment gro...

background many studies have shown that h2s protects the gastric mucosa on different models of stress but till now there are few studies about the effects of h2s on gastric acid secretion. therefore, the aim of the present study was to investigate the role of autonomic nervous system in mediating the inhibitory effect of hydrogen sulfide donor (nahs) on stimulated gastric acid secretion in rats...

Gastric endoscopy was performed in the 24 Persian Arab horses from several race training in Tehran and Tabriz for detection of gastric ulcer. Gastric ulcer was evident in 14 Persian Arab horses (58.3%). Ten out of 14 ulcers were in nonglandular region of the stomach. The horses with the history of long term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) had high prevalence of the...

background the number of patients with gastric cancer is growing worldwide. in iran (in 2009) of the 74067 new cases of cancer, 6886 were diagnosed as having gastric cancer. this study was conducted to investigate 5-year survival rate for gastric cancer in yazd province, central iran. methods in this descriptive study, the medical records of patients with gastric cancer were collected from the ...

background many studies have reported an association between periodontal infections and some systemic diseases such as respiratory and cardiovascular diseases. some studies found a direct association between chronic gastritis caused by helicobacter pylori (hp) infection and poor periodontal health. methods in a cross-sectional study from november 2014 to december 2015 in kerman, the largest pro...

background: combination chemotherapy is accepted as a high efficacy treatment for gastric cancer, whereas choice of standard treatment is unclear. multiple chemotherapeutic regimens have been used to achieve higher efficacy and lower toxicity. this study was designed to evaluate the treatment results of advanced gastric cancer with capecitabine and oxaliplatin regimen. subjects and methods : al...