The aim of the study was to investigate the effect of the antiobesity agent Garcinia cambogia extract, on serum lipoprotein (a), apolipoproteins A1 (apo A1) and B (apo B), and total cholesterol levels in atherogenic diet fed rats. Thirty female, one year old Sprague-Dawley rats were separated to three equal groups. Group 1 (control group) was fed basal diet (2% liquid vegetable oil, 0% choleste...

the aim of the study was to investigate the preventive effects of dietary garcinia cambogia extract onlipid metabolism and serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast)and gamma-glutamyle transferase (ggt) in rats fed high-lipid diet. thirty female, one-year-old sprague-dawley rats were used and separated into three equal groups. group 1 (control group) wa...

Results of recent studies on gut microbiota have suggested that obesogenic bacteria exacerbate obesity and metabolic dysfunction in the host when fed a high fat diet (HFD). In order to explore obesity-associated bacterial candidates and their response to diet, the composition of faecal bacterial communities was investigated by analyzing 16S rRNA gene sequences in mice. Dietary intervention with...

The title compound, C(32)H(49)NO(4), has been isolated from the dichloro-methane extract of the stem bark of Garcinia atroviridis Griff. ex T. Anders. Rings A and B, B and C, and C and D are trans-fused, whereas rings D and E are cis-fused. Rings A, B, C and E have slightly distorted chair conformations, while ring D is most heavily distorted towards a half-chair conformation owing to the strai...

Objectives: There is a huge demand for medicinal bark in developing countries and this demand is growing fast due to it high market values. To assess the effects of bark functions and tree capacities to recover from various debarking practices, a two-year experiment was conducted and several local harvest practices were tested on

Ten tocotrienol derivatives, i.e., amplexichromanols (1-10), were isolated from stem bark of Garcinia amplexicaulis Vieill. ex Pierre collected in Caledonia. The structures of the compounds 1-5 were determined to be chromanol derivatives substituted by a polyprenyl chain oxidized in terminal position. The remaining compounds 6-10 are the corresponding dimeric derivatives. Eleven known compounds...

CONTEXT Hydroxycitric acid, the active ingredient in the herbal compound Garcinia cambogia, competitively inhibits the extramitochondrial enzyme adenosine triphosphate-citrate (pro-3S)-lyase. As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans. OBJECTIVE To evaluate the efficac...

the aim of the study was to investigate the improving effect of garcinia cambogia extract on performance metrics, and serum non-esterified fatty acids (nefa) and c-reactive protein (crp) levels in rats fed with atherogenic diet. thirty, one-year-old, female sprague-dawley rats were randomly assigned to threeexperimental groups of ten animals each. control group was fed with basal diet (2% liqui...

Five xanthones named cowagarcinone A-E and six previously reported xanthones were isolated from the latex of Garcinia cowa Roxb. Their structures were determined on the basis of spectroscopic analysis. The crude latex and the isolated compounds were investigated for their radical scavenging activities.

Garcinia cambogia seems to promote weight reduction and improvement on lipid profile by its major compound, hydroxycitric acid (HCA), blocking ATP-citratelyase, potentially inhibiting lipogenesis. Furthermore, it is suggested that its extract is able to change the adipokine levels. Thus, the aim of this study was to analyse the effect of G. cambogia on the lipid profile, endocrine, calorimetric...