نتایج جستجو برای: ganoderic acids

تعداد نتایج: 265182  

2012
Juan Lu Jia-Zhang Qin Ping Chen Xi Chen Ying-Zhi Zhang Si-Jia Zhao

The quality difference of six varieties Ganoderma lucidum with different origins was investigated in this study by comparing the contents of ganoderic acid A and B, polysaccharide, and triterpenoids. The contents of ganoderic acid A and B in G. lucidum were analyzed by ultra performance liquid chromatography (UPLC). There was higher content of ganoderic acid A in G. lucidum of Dabie Mountain an...

2006
Wen Tang Tingyue Gu Jian-Jiang Zhong

Separation of targeted ganoderic acids from Ganoderma lucidum by reversed phase liquid chromatography with ultraviolet and mass spectrometry detections Wen Tang a, Tingyue Gu b, Jian-Jiang Zhong a,c,∗ a State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China b Department of Chemical Engineering, Ohio University, A...

2013
Bang-Jau You Miin-Huey Lee Ni Tien Meng-Shiou Lee Hui-Chuan Hsieh Lin-Hsien Tseng Yu-Lin Chung Hong-Zin Lee

Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and enhancing GA production are critical to using G. lucidum as a medicine. However, regulation of GA biosynthesis by various signaling remains poorly understood. This study investigated the role of apoptosis signaling on G...

Journal: :Molecules 2016
Xiao-Ling Wang Zhong-Yang Ding Gao-Qiang Liu Hailong Yang Guo-Ying Zhou

Triterpene acids (TAs) are the major bioactive constituents in the medicinal fungus Ganoderma lingzhi. However, fermentative production of TAs has not been optimized for commercial use, and whether the TAs isolated from G. lingzhi submerged culture mycelia possess antitumor activity needs to be further proven. In this study, enhanced TA yield and productivity were attained with G. lingzhi using...

2009
Jie Liu Jun Shiono Yukiko Tsuji Ryuichiro Kondo

Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases, and osteoclast inhibitors are the most widely used treatments for these diseases. Ganoderic acid DM, the main component of Ganoderma lucidum, has been known for its medicinal effects such as anti-androgen and anti-proliferative activities. In this study, we investigated the inhibitory effects ...

Journal: :Phytochemistry 2015
Juan Da Chun-Ru Cheng Shuai Yao Hua-Li Long Yan-Hong Wang Ikhlas A Khan Yi-Feng Li Qiu-Rong Wang Lu-Ying Cai Bao-Hong Jiang Xuan Liu Wan-Ying Wu De-An Guo

Ultra-performance liquid chromatography (UPLC) and Single Standard for Determination of Multi-Components (SSDMC) are becoming increasingly important for quality control of medicinal herbs; this approach was developed for Ganoderma lucidum. Special attention was necessary for the appropriate selection of markers, for determining the reproducibility of the relative retention times (RRT), and for ...

Journal: :Chemical & pharmaceutical bulletin 1998
B S Min N Nakamura H Miyashiro K W Bae M Hattori

Two new lanostane-type triterpenes, lucidumol A and ganoderic acid beta, were isolated from the spores of Ganoderma (G.) lucidum, together with a new natural one and seven that were known. The structures of the new triterpenes were determined as (24S)-24,25-dihydroxylanost-8-ene-3,7-dione and 3 beta,7 beta-dihydroxy-11,15-dioxolanosta-8,24(E)-dien-26-oic acid, respectively, by chemical and spec...

Journal: :applied food biotechnology 0
motaharehsadat heydarian department of life science engineering, faculty of new sciences and technologies, university of tehran, tehran, iran. ashrafalsadat hatamian-zarmi department of life science engineering, faculty of new sciences and technologies, university of tehran, tehran, iran. ghassem amoabediny department of chemical engineering, faculty of engineering, university of tehran, tehran, iran. fatemeh yazdian department of life science engineering, faculty of new sciences and technologies, university of tehran, tehran, iran. ali doryab research center for new technologies in life science engineering, university of tehran, tehran, iran.

ganoderma lucidum is one of the most well-known fungi, and has many applications in medicine. ganoderic acid is among the valuable secondary metabolites of ganoderma lucidum, and responsible for the inhibition of the tumor cell growth and cancer treatment. application of ganoderic acid has been limited because of low yields of its production from ganoderma lucidum. the present study aims to inv...

Journal: :Chemical & pharmaceutical bulletin 2009
Naoto Sato Qun Zhang Chao-Mei Ma Masao Hattori

Five new highly oxygenated lanostane-type triterpenoids [ganoderic acid GS-1 (1), ganoderic acid GS-2 (2), ganoderic acid GS-3 (3), 20(21)-dehydrolucidenic acid N (4) and 20-hydroxylucidenic acid A (5)] were isolated from the fruiting body of Ganoderma sinense, together with known compounds including 6 triterpenoids and 3 sterols. The structures of the new triterpenoids determined by spectrosco...

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