نتایج جستجو برای: gamma interferon

تعداد نتایج: 163486  

Journal: :iranian journal of virology 0
s khanizadeh department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran m ravanshad department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran sr mohebbi research center for gastroenterology and liver diseases, shahid beheshti university of medical sciences. tehran, iran h naghoosi research center for gastroenterology and liver diseases, shahid beheshti university of medical sciences. tehran, iran sd mousavinasab department of virology, school of medical sciences, tarbiat modares university, tehran, iran s romnani research center for gastroenterology and liver diseases, shahid beheshti university of medical sciences. tehran, iran

background and aims: chronic hbv infection is one of the most common viral infections in worldwide which many factors such as genetic factors are involved in pathogenesis of disease. gamma interferon (ifn-γ) and its receptor (infgr) play a critical role in the immune response to hbv infection. single nucleotide polymorphisms (snps) are effective on level of gene expression, the aim of this stud...

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ژورنال: Medical Laboratory Journal 2011
Abedian Kenary S, , Ahanjan M, , Ahmadi Basiri E, , biranvand B, , biranvand E, , Ghaheri A, , Hasannia H, , Nasrolahi M, , Parsaee MR, , Rezaee M S, ,

Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 hea...

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ژورنال: دانشور پزشکی 2012
داودی, نوشین , سلطانی نژاد, حسین , عطارپور یزدی, محمدمهدی , همتی, اعظم ,

 Background and Objective: The aim of the present study was to express recombinant human interferon-gamma in Leishmania tarentolae. The Leishmania expression system represents the combination of easy handling known from bacterial expression systems with the potential of a eukaryotic protein expression, folding and modification system. The trypanosomatid protozoan host Leishmania tarent...

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Journal: :iranian journal of allergy, asthma and immunology 0
a. farhondi n. barzargan s. arshi z. pourpak

we have reviewed the medical records of 40 patients with disseminated (bacille calmette-guerin) bcg from 1996 to 1999 in the immunology department of the children hospital, medical center, tehran university. these patients are divided in to 3 groups: 1. patients who had disseminated (bacille calmette-guerin) bcg after vaccination and their diagnosis was chronic granulomatous disease. 2. patient...

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Journal: :iranian journal of basic medical sciences 0
leila pirdel college of medicine and medical sciences, islamic azad university, ardebil branch, ardebil, iran ahmad zavaran hosseini department of immunology, school of medicine, tarbiat modares university, tehran, iran

objective(s) previous studies have demonstrated that the nitric oxide (no) dependent death of murine peritoneal macrophages activated in vitro with ifn-g and lps is mediated through apoptosis. in the present study, we investigated the synergistic effect of lps, ifn-g and iron on no production and apoptosis. materials and methods after determination of iron cytotoxicity, the peritoneal macrophag...

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Journal: :hepatitis monthly 0
reza karbasi-afshar cardiovascular diseases department, baqiyatallah university of medical sciences, tehran, ir iran amin saburi chemical injuries research center, baqiyatallah university of medical sciences, tehran, ir iran; baqiyatallah research center of gastroenterology and liver diseases (brcgl), baqiyatallah university of medical sciences, tehran, ir iran; chemical injuries research center and baqiyatallah research center of gastroenterology and liver diseases (brcgl), baqiyatallah university of medical sciences, mollasadra st, vanaksq, tehran, ir iran. tel/fax: +98-2188600067

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Journal: :jundishapur journal of microbiology 0
yahya maroufi department of parasitology, faculty of medical sciences, zabol university of medical sciences, zabol, ir iran fatemeh ghaffarifar department of parasitology, faculty of medical sciences, tarbiat modares university, tehran, ir iran; department of parasitology, faculty of medical sciences, zabol university of medical sciences, zabol, ir iran. tel: +98-2182884553, fax: +98-2188006544 abdolhosein dalimi department of parasitology, faculty of medical sciences, tarbiat modares university, tehran, ir iran zohreh sharifi department of virology, iranian blood transfusion organization, tehran, ir iran

background cutaneous leishmaniasis is a health problem in the world. lesions should be treated on cosmetically or functionally important sites, such as the face and hands. cantharidin is a terpenoid compound produced naturally by beetles of meloidae and oedemeridae families. objectives the current study aimed to investigate the effect of cantharidin on cutaneous leishmaniasis (cl) lesions and i...

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Journal: :jundishapur journal of microbiology 0
nadia ghasemian medical cellular & molecular research center, golestan university of medical sciences, gorgan, ir iran majid shahbazi medical cellular & molecular research center, golestan university of medical sciences, gorgan, ir iran; medical cellular & molecular research center, golestan university of medical sciences, gorgan, ir iran. tel/fax: +98-1732421657

results the frequencies of the aa, at, and tt genotypes were 31%, 51%, and 18% in the chronic hbv patient group, and 40%, 45%, and 15% in the healthy control group, respectively. however, a lack of association of the + 874 polymorphism in the ifn-γ gene of those with chronic hbv infection was found. evaluation of hbv association with this polymorphism was significant under the dominant genetic ...

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Journal: :iranian biomedical journal 0
آمینا کریمی نیا amina kariminia سوسن کبودیان اردستانی sussan k. ardestani نرگس السادات اردستانی nargess al-sadat ardestani حوریه سپهری houri sepehry هایده دارابی haideh darabi

it is now well documented that interferon gamma (ifn-γ) is the indispensable cytokine for inducing protective immunity against experimental and human cutaneous leishmaniaisis. the importance of ifn-γ receptor (ifn-γr) has also been studied. in the present study, we made attempts to find out whether l. major infection is able to alter the expression of ifn-γr in vivo. in addition, we studied the...

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Journal: :iranian journal of basic medical sciences 0
soodeh razeghi jahromi multiple sclerosis research center-neuroscience institute, sina hospital, tehran university of medical sciences, tehran, iran shefa neuroscience research center, tehran, iran seyed rafi arrefhosseini department of nutrition and health, tabriz university of medical sciences amir ghaemi department of virology, school of medicine, golestan university of medical sciences, gorgan, iran shefa neuroscience research center, tehran, iran akram alizadeh department of tissue engineering , faculty of advanced medicine and technology, tehran university of medical sciences, tehran, iran fateme sabetghadam dvm, faculty of veterinary medicine, ferdowsi university of mashhad, mashhad , iran mansoureh togha 7 department of neurology, iranian center of neurological research-neuroscience institute, sina hospital, tehran university of medical sciences, tehran, iran

objective(s):experimental allergic encephalomyelitis (eae) is an autoimmune disease validated as animal model of multiple sclerosis (ms). administration of genistein, a phytoestrogenic component of soy, to mice at the onset of eae is known to attenuate the clinical signs of the disease. the potential effects of genistein on established eae is less studied. in the current study, we aimed to comp...

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