Background: Previous investigations have revealed, cimetidine, a histamine H2-receptor antagonist, show radioprotective effects against gamma- and neutron-induced micronuclei in bone marrow erythrocytes. In this study, the anticlastogenic effects of famotidine and ranitidine, which act similar to cimetidine as histamine H2-receptor antagonists, was investigated. Materials and Methods : Balb/c m...

Background: During radiation therapy, stromal cells surrounding the tumor (e.g mesenchymal stem cells) may affect the treatment outcomes. We aimed to investigate the effects of gamma radiation on the mRNA expression of cytokines, DNA damage and population doubling time (PDT) of adipose-derived mesenchymal stem cells (ASCs). Material and methods: ASCs were enzymatically extracted from breast tis...

The limited germplasm resources of hulless barley restrict the breeding with improved traits. Mutation techniques are an effective tool for generating variation plant studies. This study aimed to evaluate impact gamma-ray at different doses on certain seedling properties M1 plants two genotypes, as well determine dose (ED50). seeds two-row cv. Yalin and line YAA7050-14, were irradiated 100, 150...

The aim of present study was to investigate the potential antioxidant and lung protective activities of Sambucus ebulus (SE) against toxicity induced by gamma irradiation. Hydroalcoholic extract of SE (20, 50 and 100 mg/kg) was studied for its lung protective activity. Phenol and flavonoid contents of SE were determined. Male C57 mice were divided into ten groups with five mice per group. Only ...

The soybean (Glycine max l. merr) is one of oil seed plants from leguminous family. In this study, the effect of gamma radiation on chlorophyll, soluble and insoluble carbohydrate and composition oil seeds were investigated in soybean. Soybean variety J.K was irradiated with 0,100,200 and 300 gamma ray. The treatment and control seeds planed in with four replicates. The highest amount of total ...

In order to study the effects of gamma rays on mean germination time (MGT), germination percentage, survival percentage, shoot and root length and, number of branches and leaves per plant, and fresh and dry weight of Lepidium sativum L current experiment was conducted. Dry seeds of Lepidum sativum L were irradiated with 20, 30, 40, 50, 60, 70 and 80 krad (Kr) by a Co-gamma chamber at Nuclear In...

abstract background: radiosensitizer drugs are used to enhance the efficiency of radiotherapy. some nanoparticles can be considered as radiosensitizers, because they enhance cytotoxicity due to oxidative stress and increase free radical yield, especially ros , within cells resulting to cell death. methods: in this study, synergistic effect of tio 2 nanoparticles was evaluated in presence of 60 ...