We report three cases of invasive Geotrichum capitatum infection in patients with acute leukemia for which an enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Supernatants obtained from suspensions of 17 G. capitatum strains gave positive reactions with the Aspergillus galactomannan ELISA. These clinical and laboratory data...

To the Editor—We read the article by Maertens et al [1] with great interest. In a series of 58 patients who received a diagnosis of proven or probable invasive aspergillosis (IA), the authors confirmed previous work that the diagnostic performance of galactomannan antigen levels in bronchoalveolar lavage (BAL) fluid samples is good and that the procedure is safe in critically ill hematology pat...

To the Editor—We read the article by Maertens et al [1] with great interest. In a series of 58 patients who received a diagnosis of proven or probable invasive aspergillosis (IA), the authors confirmed previous work that the diagnostic performance of galactomannan antigen levels in bronchoalveolar lavage (BAL) fluid samples is good and that the procedure is safe in critically ill hematology pat...

We report a case of cryptococcosis in which a serum enzyme-linked immunosorbent assay (ELISA) for Aspergillus galactomannan was positive, with no evidence of aspergillosis. Soluble antigens from 19 Cryptococcus neoformans strains and purified carbohydrates of C. neoformans capsule were thus assayed in the Aspergillus galactomannan ELISA. Antigens from all C. neoformans strains, and purified gal...

Objectives : The purpose of this study was to evaluate the mutagenic potential fluoxetine and fluoxetine-galactomannan. Methods Chromosomal aberration test Salmonella typhimurium/microsome mutagenicity assay. Results results showed that (250 μg/mL) can cause chromosomal breaks treated leukocytes increase frequency reversion tester strains S. typhimurium / microsome assay only at highest concent...

BACKGROUND Infections are an important cause of morbidity and mortality in patients with rheumatoid arthritis. Patients receiving immunosuppressive or anti-tumor necrosis factor (TNF) agents are vulnerable to fungal infections, including those derived from Aspergillus species. Detection of the Aspergillus galactomannan antigen in serum is useful for the early diagnosis of invasive aspergillosis...

Comments on ''Detection of galactomannan in the bronchoalveolar lavage of high-risk patients with invasive aspergillosis admitted at the intensive care unit'' by Khodavaisy et al.  AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP    AWT-SEP  Galactomannan in bronchoalveolar lavage for diagnosis of invasive aspergillosis  We rea...

INTRODUCTION Invasive aspergillosis is a condition associated with a high mortality rate mostly due to difficulties in performing an early diagnosis. In recent years, galactomannan detection has markedly improved the diagnosis of invasive aspergillosis, but very little is known on how physicians deal with this test in clinical practice. METHODS This cross-sectional study aimed to analyze the ...

This study investigated the effects of galacomannans (guar gum, tara gum, and locust bean gum) on the rheological properties of buckwheat starch pastes under steady and dynamic shear conditions. The power law and Casson models were applied to describe the flow behavior of the buckwheat starch and galactomannan mixtures. The values of the apparent viscosity (ηa,100), consistency index (K), and y...

Choosing a prophylactic approach is a strategic decision impacting the choice, timing, and even the indication of in vitro diagnostic tests and antifungal treatments. In the past, clinical studies informing clinical decisions were conducted in settings without prophylaxis. One may object, that empiric antifungal treatment trials allowed enrolling patients on antifungal prophylaxis with fluconaz...