There is an increasing need for accurate prediction methods of assessing individual risk for breast cancer for both clinical and research purposes. The purpose of this study is to compare the Gail and Claus model risk estimates of breast cancer among women with a family history of breast cancer. This study presents risk estimates from two models of breast cancer risk in 491 women 18 to 74 years...

BACKGROUND Recent guidelines suggest that chemoprevention with tamoxifen may be appropriate for women who have a 5-year risk of breast cancer greater than 1.66% calculated using the Gail model. OBJECTIVES To determine whether nipple aspirate fluid (NAF) cytology combined with the Gail model provides breast cancer risk assessment that is superior to either method alone. METHODS Prospective o...

BACKGROUND Breast cancer is the most frequently diagnosed malignancy among Chilean women and an increasingly significant public health threat. This study assessed the accuracy of breast cancer risk perception among underserved, Chilean women. METHODS Women aged 50 to 70 years, with no mammogram during the last 2 years, were randomly selected from a community clinic registry in Santiago, Chile...

The Wada Test (WT) is part of the presurgical evaluation for refractory epilepsy. The WT is not standardized and the protocols differ in important ways, including stimulus type of material presented for memory testing, timing of presentations and methods of assessment. The aim of this study was to contribute to establish parameters for a WT to Brazilian population investigating the performance ...

Background: Breast cancer is one of the most important malignancies in both developed and developing countries. Objectives: To reduce the burden of this disease, the prediction of individuals at risk and implementation of efficient preventive interventions can be effective. The present study was aimed at investigating five-year and lifetime risks of the breast cancer in a rural community in Za...

Gail Wilkes, RNC, MS, AOCN®, is an oncology nurse educator at Boston Medical Center in Massachusetts. Wilkes is a member of the speaker’s bureau for Sanofi-Synthelabo, Inc., the manufacturer of oxaliplatin (EloxatinTM). (Mention of specific products and opinions related to those products do not indicate or imply endorsement by the Clinical Journal of Oncology Nursing or the Oncology Nursing Soc...

BACKGROUND The Gail model is a validated breast cancer risk assessment tool that is primarily based on nonmodifiable breast cancer risk factors. Conversely, mammographic breast density is strongly correlated with breast cancer risk and responds to risk-modifying interventions. The purpose of our study was to correlate mammographic density with breast cancer risk as calculated by the Gail model ...

Imitation learning is a branch of reinforcement learning that aims to train an agent to imitate an expert’s behaviour, with no explicit reward signal or knowledge of the world. Generative Adversarial Imitation Learning (GAIL) is a recent model that performs this very well, in a data-efficient manner. However, it has only been used with low-level, low-dimensional state information, with few resu...

In a Perspective, Linda-Gail Bekker and Glenda Gray discuss HIV vaccine development.