Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common disease of the hexose monophosphate pathway existing in more than 400 million people worldwide. The aim of this study was to identify neonates with G6PD deficiency following national program for screening and education of affected newborns’ parents started since June 2007 in Mazandaran, a northern Province of Ira...

background: glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most common disease of the hexose monophosphate pathway existing in more than 400 million people worldwide. the aim of this study was to identify neonates with g6pd deficiency following national program for screening and education of affected newborns’ parents started since june 2007 in mazandaran, a northern province of ira...

OBJECTIVE To evaluate the correlation between glucose-6-phosphate-dehydrogenase (G6PD) deficiency and neonatal jaundice. METHODS Prospective, observational case-control study was conducted on 490 newborns admitted to Hospital de Clínicas de Porto Alegre for phototherapy, who all experienced 35 or more weeks of gestation, from March to December 2007. Enzymatic screening of G6PD activity was pe...

Objective: To determine the frequency of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in neonates presenting with jaundice. Material and Methods: This descriptive study was conducted at Special Care Baby Unit (SCBU) Department of Child Health, Khyber Teaching Hospital, Peshawar from January 2008 to June 2008. A total number of 283 newborns, aged 1-14 days of either sex admitted with jaun...

To establish the neonatal screening method of glucose-6 phosphate dehydrogenase (G6PD) deficiency, G6PD activity was measured using the fluorescence spot test (FST) using dried blood samples on filter paper. The G6PD/6PGD rate test of venous blood samples was further performed for confirmation. The positive G6PD deficiency rate was 4.2% and its detection rates were 3.7% for all neonates and 5.2...

For the implementation of the neonatal screening program, the following factors have to be considered for the selection of conditions to be screened and evaluation of outcome. These include the factors pertaining to public health impact, availability and acceptability of the screening system, and other social issues involved in the implementation. In the context of Hong Kong, Glucose-6-Phosphat...

Glucose-6-phosphate dehydrogenase (G6PD) is the initial enzyme in the hexose monophosphate pathway of glucose metabolism. Deficiency of G6PD has been linked to increased sensitivity of red cells to hemolytic anemia due to certain oxidant drugs, infectious agents or fava beans. It is an inherited error in metabolism and has a high incidence in certain ethnic groups. Astoria-Pacific has developed...

BACKGROUND There is a strong correlation between glucose-6-phosphate dehydrogenase (G6PD) deficiency and neonatal hyperbilirubinemia with a rare but potential threat of devastating acute bilirubin encephalopathy. G6PD deficiency was observed in 4-14% of hospitalized icteric neonates in Pakistan. G6PD c.563C > T is the most frequently reported variant in this population. The present study was ai...