It is well established that during cell secretion, membrane bound secretory vesicles dock and fuse at the base of supramolecular cup shaped structures at the cell plasma membrane called “porosomes”, to expel intra vesicular contents to the outside. In neurons, it has been demonstrated that 12–17 nm cup shaped lipoprotein structure possessing a central plug are present at the presynaptic membran...

Porosomes are proposed to be the universal secretory machinery of the cell plasma membrane, where membrane-bound secretory vesicles transiently dock and fuse to expel their contents to the extracellular space during cell secretion. In neurons, porosomes are manifested as cup-shaped lipoprotein structures in the presynaptic membrane, 12-17 nm in diameter and possessing a central plug. Hair cells...

introduction: the ideal endodontic treatment for the teeth with in complete root-ends and necrotic pulps may involve the use of material which forms an immediate apical barrier instead of long term calcium hydroxide therapy. such procedure may lead us to a single appointment endodontic treatment. the purpose of the present study was to evaluate clinical and radiographic success rate in necrotic...

Not every file presented by a computer operating system needs to be an actual stream of independent bits. We demonstrate that different types of virtual files and folders including so-called “Filesystems in Userspace” (FUSE) allow streamlining audio content management with relatively little additional complexity. For instance, an off-the-shelf database system may present a distributed sound lib...