microbial steroid biotransformation have found wide-reaching application for the production of more precious and functionalized compounds due to their high regio-and stereoselectivity. in this study, the possibility of using filamentous fungi aspergillus brasiliensis cells in the biotransformation of progesterone (i), a c-21 steroid hormone was studied for the first time.the fungal strain was i...

Taxifolin is known to have multiple biological functions. It has been widely used as a multifunctional food additive, and consequently, the global demand for taxifolin increasing. The main method production an extraction from larch wood, but resources of are limited. Astilbin, taxifolin-3-o-rhamnoside, abundant in many plants much more readily available, meaning can be obtained by deglycosylati...

Sinapic acid biotransformation was studied and screened using eleven fungal cultures. Penicillium chermesinum AUMC 275, Aspergillus ochraceus 11328, Paecilomyces variotii 5618 showed positive results in the production of metabolites. resulted gallic after 10 days incubation with P. chermesinum, protocatechuic 7 A. ochraceus, ferulic 5 variotii. The investigated compounds' a

To produce an active metabolite of Chlordiazepoxide by fungal biotransformation in easy and economic way also to develop microbial models for drug metabolism studies. is metabolized the liver CYP3A4 forms major N-desmethyl chlordiazepoxide. The focus study was explore ability six distinct fungi biotransform its metabolites. Induction, Inhibition kinetic studies were conducted find out type capa...

The present investigation was aimed at studying the effect of incubation period, media, vitamins and solvents on biotransformation of albendazole by Cunninghamella blakesleeana. The transformation was evaluated and identified by high performance liquid chromatography (HPLC) and the structures of the transformed products were assigned by liquid chromatography-tandem mass spectrometry (LC/MS/MS) ...

In order to select microorganisms capable of transforming the potent phytoestrogen 8-prenylnaringenin, preliminary screening tests on 30 fungal cultures were performed. No reports concerning successful biotransformation of 8-prenylnaringenin by this class of organisms have been known so far. Fusarium equiseti converted 8-prenylnaringenin into

A total of 40 fungal cultures were isolated for their ability to grow on caffeine as a sole source carbon and nitrogen, and further screened for theophylline-producing activities under the growing cell system. Based on thin-layer chromatography and high-performance liquid chromatography analyses, the potent strain Aureobasidium sp. TeO12 was chosen for its capability to generate theophylline vi...