نتایج جستجو برای: fragmented dna

تعداد نتایج: 520217  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Søren Overballe-Petersen Klaus Harms Ludovic A A Orlando J Victor Moreno Mayar Simon Rasmussen Tais W Dahl Minik T Rosing Anthony M Poole Thomas Sicheritz-Ponten Søren Brunak Sabrina Inselmann Johann de Vries Wilfried Wackernagel Oliver G Pybus Rasmus Nielsen Pål Jarle Johnsen Kaare Magne Nielsen Eske Willerslev

DNA molecules are continuously released through decomposition of organic matter and are ubiquitous in most environments. Such DNA becomes fragmented and damaged (often <100 bp) and may persist in the environment for more than half a million years. Fragmented DNA is recognized as nutrient source for microbes, but not as potential substrate for bacterial evolution. Here, we show that fragmented D...

Journal: :Chemical communications 2011
Rui Cao Baoxin Li Yuanfu Zhang Zhining Zhang

Positively-charged gold nanoparticles can effectively differentiate long DNA and fragmented DNA, thus providing a simple and visual approach to colorimetric detection of nuclease activity.

Journal: :Proceedings of the National Academy of Sciences 2018

With the advance in nanomedicine, the present study was conducted to explore the possible therapeutic role of intravenous nano- hydroxyapatite (nano-HAp) into male rats after chronic exposure to aluminum chloride (AlCl3). This exposure interposed DNA fragmentation, apoptosis, alters oxidant/antioxidant status as well as change in content of neurotransmitters. The rats were injected with 100 mg/...

With the advance in nanomedicine, the present study was conducted to explore the possible therapeutic role of intravenous nano- hydroxyapatite (nano-HAp) into male rats after chronic exposure to aluminum chloride (AlCl3). This exposure interposed DNA fragmentation, apoptosis, alters oxidant/antioxidant status as well as change in content of neurotransmitters. The rats were injected with 100 mg/...

2015
Kentaro Yoshida Eriko Sasaki Sophien Kamoun

The application of DNA sequencing technology to the study of ancient DNA has enabled the reconstruction of past epidemics from genomes of historically important plant-associated microbes. Recently, the genome sequences of the potato late blight pathogen Phytophthora infestans were analyzed from 19th century herbarium specimens. These herbarium samples originated from infected potatoes collected...

Journal: :The Journal of endocrinology 2004
R Otton F G Soriano R Verlengia R Curi

The occurrence of DNA fragmentation in lymphocytes obtained from alloxan-induced diabetic rats and diabetic patients was investigated. A high proportion of apoptotic lymphocytes in diabetic states may explain the impaired immune function in poorly controlled diabetic patients. Rat mesenteric lymph node lymphocytes were analysed for DNA fragmentation by using flow cytometry and agarose gel, and ...

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