OBJECTIVE To evaluate whether mandatory fortification of grain products with folic acid in the US is associated with changes in histone methylation in cells involved in cervical carcinogenesis. METHODS Cervical specimens obtained before (1990 to 1992) and after mandatory folic acid fortification (2000 to 2002) were used to examine the degree of histone methylation (H3 Lys-9) by immunohistoche...

OBJECTIVE To assess the level of hemoglobin-Hb during pregnancy before and after fortification of flours with iron. METHOD A cross-sectional study with data from 12,119 pregnant women attended at a public prenatal from five macro regions of Brazil. The sample was divided into two groups: Before-fortification (birth before June/2004) and After-fortification (last menstruation after June/2005)....

BACKGROUND One-third of the world's population suffers from micronutrient deficiencies due primarily to inadequate dietary intake. Food fortification is often touted as the most promising short- to medium-term strategy for combating these deficiencies. Despite its appealing characteristics, progress in fortification has been slow. OBJECTIVE To assess the potential of household food-purchase d...

This article reviews the current landscape regarding food fortification in the United States; the content is based on a workshop sponsored by the North American Branch of the International Life Sciences Institute. Fortification of the food supply with vitamins and minerals is a public health strategy to enhance nutrient intakes of the population without increasing caloric intake. Many individua...

In a recent work, Moshkovitz [FOCS ’14] presented a transformation on two-player games called “fortification”, and gave an elementary proof of an (exponential decay) parallel repetition theorem for fortified two-player projection games. In this paper, we give an analytic reformulation of Moshkovitz’s fortification framework, which was originally cast in combinatorial terms. This reformulation a...

BACKGROUND Vitamins and minerals are essential for growth and metabolism. The World Health Organization estimates that more than 2 billion people are deficient in key vitamins and minerals. Groups most vulnerable to these micronutrient deficiencies are pregnant and lactating women and young children, given their increased demands. Food fortification is one of the strategies that has been used s...

CONTEXT Daily consumption of 400 microg of folic acid before conception and during early pregnancy dramatically reduces the occurrence of neural tube defects (NTDs). Before food fortification, however, only an estimated 29% of US reproductive-aged women were taking a supplement containing 400 microg of folic acid daily. The US Food and Drug Administration authorized addition of folic acid to en...

BACKGROUND Flour fortification with folic acid is one of the main strategies for improving folate status in women of childbearing age. No interventional trial on the efficacy of folic acid fortification has been conducted so far in Iran. OBJECTIVES To study the effects of flour fortification with folic acid on any reduction in neural tube defects (NTDs) and folate status of women of childbear...

Background: There has been a concern regarding the masking of vitamin B-­‐12 deficiency in the post-­‐fortification period (after January 1, 1998). Objective: The objective of this study was to investigate the potential masking of vitamin B-­‐12 deficiency by comparing the proportion ...

Vitamin D deficiency is widely prevalent in India, despite abundant sunshine. Fortification of staple foods with vitamin D is a viable strategy to target an entire population. Vitamin D fortification programs implemented in the United States and Canada have improved the vitamin D status in these countries, but a significant proportion of the population is still vitamin D deficient. Before forti...