1. In this study mast cells were found to comprise 2.1% of total cells recovered by enzymatic digestion of human lung tissue. 2. This mast cell population consisted of 79% formalin-sensitive, Alcian Blue-positive mast cells and 21% formalin-insensitive, Alcian Blue-positive mast cells. 3. By the use of centrifugal elutriation and subsequent Percoll gradient centrifugation, separate mixed cell p...

Background: Fixation of biopsy specimens is a critical step before processing and staining them for histological tissue examination. Formalin considered the gold standard fixative solution its attributes. However, it has concerning side effects, such as carcinogenic potential irritational properties. Owing to various harmful safer natural substitute should be explored. In this study, we compare...

Background: An accurate histopathological assessment and reporting of testicular biopsies require an appropriate tissue fixative. We assessed the histological, histochemical, immunohistochemical quality biopsies, comparing 10% formalin versus Bouin solution as fixatives. Methods: This experimental study utilized 20 adult male albino rats equally divided into five cages for 30 days. By end exper...

ABSTRAK
 
 Penggunaan Boraks di Indonesia, seperti yang dinyatakan oleh surveilans Keamanan Pangan Badan Pengawasan Obat dan Makanan (BPOM) RI tahun 2009 bahwa penggunaan bahan toksik Indonesia telah mencapai 8,80%. Pada Wilayah Tangerang juga ditemukan sebanyak 25 sampel bakso positif mengandung (25%) rata-rata kandungan boraksnya adalah 806,86 mg/kg.
 Untuk mengetahui Pengaruh ...

INTRODUCTION Formalin injection induces nociceptive bahaviour in phase I and II, with a quiescent phase between them. While active inhibitory mechanisms are proposed to be responsible for initiation of interphase, the exact mechanisms which lead to termination of nociceptive response in phase II are not clear yet. Phase II is a consequence of peripheral and central sensitization processes, whic...

background: musculoskeletal pain is a major clinical problem, but researchers lack viable animal models to study this phenomenon. however, formalin injections are widely used to produce tonic and neurogenic nociceptive responses in rodents. rodents can present a potential animal model for pain. objectives: to develop a muscle pain model with intramuscular injection of formalin in rats. material...

Intraplantar formalin injection is widely used as an experimental model of tonic pain. We investigated the role of endogenous A-opioid receptor mechanisms in formalin-induced nocifensive behavior in mice. The flinching response induced by formalin (2%, 20 Al) was studied in mice with normal (wild type, n = 8) and absent (homozygous A-opioid receptor knockout, n = 8) A-opioid receptor levels. Th...

Precise surgical excision of brain tumors depends on the surgeon’s ability to accurately differentiate from healthy tissues. We have developed an automated system integrated with biochips, actuation unit, and electronics measure electrical resistivity ex vivo human tissues for differentiating normal tumor. The fresh (n = 48), formalin-fixed one week long-term (six months) 27) samp...

Introduction: The health hazards resulting from exposure to formalin have given rise the need of developing safer alternative fixatives. Almond oil has been widely used in aromatherapy and cosmetic industry for its good penetrating skin-rejuvenating properties, whereas vitamin E is a known anti-oxidant. present study aimed test fixative efficacy almond with as compared formalin.
 Material ...