BACKGROUND The diagnosis of thyroid follicular carcinoma by fine needle aspiration biopsy is a well known problem in thyroid pathology. METHODS We evaluated telomerase activity (TA) in 85 fine needle aspiration biopsy (FNAB) samples from patients with thyroid nodules. Surgery samples from patients with tumor or follicular adenomas were also analyzed. RESULTS Twenty of the FNAB samples corre...

OBJECTIVE To show the benefits of fine-needle aspiration biopsy (FNAB) in managing thyroid nodules. METHODS As a retrospective study, reports of 888 FNABs of the thyroid performed during a period of 11 years (1996-2007) at Tehran University of Medical Sciences, Sina Hospital and Endocrine Clinic, Tehran, Iran were reviewed. Histological diagnoses were available for 182 cases, and we compared ...

PURPOSE Thyroid nodules are common, with a lifetime risk of developing a clinically significant thyroid nodule of 10% or higher. Preoperative diagnosis was greatly enhanced by the introduction of fine needle aspiration in the 1970s, but there has been little advancement since that time. Discrimination between benign and malignant follicular neoplasms is currently not possible by fine needle asp...

In Riedel’s thyroiditis, a rare chronic inflammatory disease of thyroid gland, fine needle aspiration is usually non-diagnostic because most often only follicular cells are obtained and not the fibrous material characteristic of this type of thyroiditis. Therefore the diagnosis is often only established by histopathologic study of the surgically obtained biopsy. The illustrated case is a 46-yea...

introduction: to determine the prevalence of oocyte pick up complications in 1120 cycles of ivf . material and methods: in this prospective study 1120 pationts that were reffered to infertility clinics for ivf were enrolled. the patients with the infertility following co4 by regimens of cc+ hmg/hcg, hmg/hcg, hmg+ gnrh-a/hcg were punctured by transvaginal sonography, preformed after injection of...

The distinction of benign from malignant follicular thyroid neoplasms remains a difficult task in diagnostic fine-needle aspiration cytology, and some discrepant results have been reported for the individual immunocytochemical markers of malignancy proposed so far. The aim of this study was to test if the combined use of a panel of markers could improve the diagnostic accuracy in the preoperati...

Fine needle aspiration biopsy (FNAB) of the thyroid is limited in distinguishing hyperplastic nodular goiter from true follicular neoplasm and in separating follicular adenoma from follicular carcinoma. The present study was done to evaluate if the morphologic and morphometric investigations and silver staining of nucleolar organizer regions (NORs), either alone or in association would help to ...

in riedel’s thyroiditis, a rare chronic inflammatory disease of thyroid gland, fine needle aspiration is usually non-diagnostic because most often only follicular cells are obtained and not the fibrous material characteristic of this type of thyroiditis. therefore the diagnosis is often only established by histopathologic study of the surgically obtained biopsy. the illustrated case is a 46-yea...

Galectin-3 is a carbohydrate-binding protein endowed with an affinity for beta-galactosides. It has been shown to play an important role in cell-cell and cell-matrix interactions and in pre-mRNA splicing. Furthermore, it is involved in the control of cell growth, neoplastic transformation, and metastasis. Interestingly, high levels of galectin-3 expression have been recently described in malign...

Thyroid cancer accounts for approximately 1% of all human cancers. Follicular carcinoma thyroid (FCT) is the second most common thyroid cancer after papillary carcinoma. Follicular carcinoma thyroid accounts for 10-15% of clinically evident thyroid malignancies. Follicular carcinoma thyroid commonly metastasize to lung and bone. Intracranial metastasis occurs in about only 1%. Follicular carcin...