Acetone extracts of selected plant species were evaluated for their in vitro cytotoxicity against a noncancerous African green monkey kidney (Vero) cell line and an adenocarcinoma cervical cancer (HeLa) cell line. The plants studied were Origanum vulgare L. (Oregano), Rosmarinus officinalis L. (Upright and ground cove rosemary), Lavandula spica L. (Lavender), Laurus nobilis L. (Bay leaf), Thymu...

This protocol describes the state of knowledge on safety in use preparations from fruits sweet and bitter fennel (Foeniculum vulgare Mill. Foeniculum piperitum (Ucria) C.Presl) at time drafting before full assessment is carried out, outlines questions sub-questions, specifies evidence needs, provides a detailed plan for assessment. It applied to first three risk steps: hazard identification, ch...

Essential oils of the fruits of three organically grown cultivars of Egyptian fennel (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce and Foeniculum vulgare var. vulgare) were examined for their chemical constituents, antimicrobial and antioxidant activities. Gas chromatography/mass spectrometry analysis of the essential oils revealed the presence of 18 major monoterpenoids in a...

A case report (two patients) of accidental intoxication occurred in Northern Italy. Conium maculatum L. (poison hemlock) leaves were confused with and collected as Foeniculum vulgare Mill. (sweet fennel). C. maculatum contains piperidine alkaloids: coniine, N-methylconiine, conhydrine, pseudoconhydrine and -coniceine, toxic to human beings. Identification and microscopic examination of the cons...

PURPOSE Evaluation of oculohypotensive activity of single drop application of aqueous extract of Foeniculum vulgare in experimental models of glaucoma. METHODS The evaluation of oculohypotensive activity of Foeniculum vulgare was done in rabbits with normal intraocular pressure (IOP) and with experimentally elevated IOP. The experimental increase in IOP was achieved using water loading and st...