The modeling of 3D Compton scatter in SPECT is complicated by the use of a variety of collimator geometry. To date, effective and efficient modeling of 3D Compton scatter in parallel-beam SPECT has been made possible by Frey and Tsui [1], Zeng et al [2], and Bai et al [3]. For fan-beam and cone-beam SPECT, the model in [3] can effectively model first order 3D Compton scatter. But for varying-fo...

99mTc methoxyisobutylisonitrile planar scintimammography (SMM) is mostly performed using low-energy high-resolution (LEHR) parallel collimators. We studied whether using a different collimator could improve the detection of small (< 1.5 cm) lesions for which SMM sensitivity is poor. Thirty four breast phantom configurations were considered, either with hot spheres simulating lesions or without ...

The authors present a new method to compensate for the spatially variant detector response in single photon emission computed tomography (SPECT) with varying focal-length fan-beam (VFF) geometry. In this method, the deblurred projection is explicitly expressed as an integral of the collimator blurred data and the fully calibrated system kernel matrix with certain transforms. It needs a little m...

Single photon emission computed tomography (SPECT) is based on the measurement of radiation emitted by a radiotracer injected into the patient. Because of photoelectric absorption and Compton scatter, the gamma photons are attenuated inside the body before arriving at the detector. A quantitative reconstruction must consider the attenuation, which is usually nonuniform. Novikov has derived an e...

Objective(s): A novel IQ-SPECTTM method has become widely used in clinical studies. The present study compares the quality of myocardial perfusion images (MPI) acquired using the IQ-SPECTTM (IQ-mode),conventional (180° apart: C-mode) and L-mode (90° apart: L-mode) systems. We assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. Materials and Me...

The pinhole collimator is currently the collimator of choice in small animal single photon emission computed tomography (SPECT) imaging because it can provide high spatial resolution and reasonable sensitivity when the animal is placed very close to the pinhole. It is well known that if the collimator rotates around the object (e.g., a small animal) in a circular orbit to form a cone-beam imagi...

The SLC final-focus system accommodates 29 fixed or adjustable collimators for machine protection and background reduction. By amplifying pulse-to-pulse orbit variations and by generating emittance growth, collimator wake fields may degrade the beam quality at the interaction point (IP). In the SLC final focus, collimator halfapertures are larger than the bunch length, so that the standard coll...

Images generated with helical scanning are degraded by partial volume artifacts caused by an increased slice thickness when compared to conventional computed tomography (CT) scanning. The slice thickness for a helical scan is proportional to the sum of the thickness of the fan of radiation and the distance the patient moves during data acquisition. We present a method called moving beam helical...