Determination of terazosin hydrochloride dihydrate (TRZ) in drug substance and tablets was studied by fluorimetric techniques. The fluorimetric methods are based on: (1) measurement of the native fluorescence of the drug in water at 750 nm after excitation at 330 nm. (2) sensitizing the native fluorescence by formation a binary complex of drug with aqueous uranyl acetate (0.1% w/v) at the same ...

Phytic acid exerts an activation effect on the oxidation of 2,2'-dipyridyl ketone hydrazone catalysed by Cu(II) ion and the oxidation product is highly fluorescent. A fixed time method for the fluorimetric determination of phytic acid based on this effect is described. The calibration graph is linear over the range 0.05-0.6 mg l-1 phytic acid, resulting in a limit of detection of 0.03 mg l-1 ph...

This paper proposes new methods for simple and sensitive spectrophotometric and fluorimetric determination of naltrexone (NALT) in tablet and biological fluids. The spectrophotometric method involve addition of a known excess of Ce(IV) to NALT in acid medium, followed by determination of residual Ce(IV) by reacting with a fixed amount of methyl orange, and measuring the absorbance at 510 nm. Fl...

A spectrofluorimetric method to determine tacrine is proposed and applied to the determination of tacrine in human serum and pharmaceuticals. The fluorimetric method allows the determination of 1-70 ng ml-1 of tacrine in aqueous solutions containing acetic acid-sodium acetate buffer (pH 5.6) with lambda exc = 242 nm and lambda em = 362 nm.

A sensitive fluorimetric method was developed for the quantitative determination of DNA in plant (Zea mays L. and Medicago sativa L.) extracts. This method takes advantage of the specific increase in fluorescence intensity of the complex of DNA and the dye 4',6'-diamidino-2-phenylindole (DAPI). Recovery of DNA and dissociation of histones from DNA were maximized by the addition of 2.0 molar NaC...

soluble vitamin and needed for the growth and repair of tissues in all parts of the body. AA has vital importance in processes of oxidation and reduction in human organism participating of several metabolic reactions. AA has also been used for the prevention and treatment of the common cold, mental illness, infertility, cancer and AIDS. Due to the great importance of AA in human beings, the qua...