Flavonols are one of the largest groups of flavonoids that confer benefits for the health of plants and animals. Flavonol glycosides are the predominant flavonoids present in the model legume Lotus japonicus. The molecular mechanisms underlying the biosynthesis of flavonol glycosides as yet remain unknown in L. japonicus. In the present study, we identified a total of 188 UDP-glycosyltransferas...

Cranberry is reported to have health benefits including prevention of urinary tract infections and other chronic diseases, due to the high content of polyphenols including flavonols and flavan-3-ols. The aim of this study was to determine the clearance of flavonol glycosides and flavan-3-ols and/or their metabolites in human urine. Ten healthy women volunteers ingested 240 ml cranberry juice co...

A rapid microwave-assisted hydrolysis (MAH) method is presented for the sample pretreatment of the determination of ginkgo flavonol glycosides in extracts of Ginkgo biloba L. (EGb). By this method, flavonol glycosides can be completely hydrolyzed within 2 min. After investigating the effects of solvents, acidity, microwave power, and microwave radiation time on hydrolysis, the optimal hydrolysi...

Frozen blueberries (Vaccinium corymbosum L.) were processed into juice and concentrate, and the changes in anthocyanin pigments and polyphenolics (cinnamates, procyanidins, flavonol glycosides) were monitored. While juice yield was 83%, only 32% of the anthocyanins were recovered in single-strength juice. Flavonol, procyanidin and chlorogenic acid recoveries in juice were 35%, 43%, and 53%, res...

Four clerodane glycosides, cussosides A-D, and one labdane glycoside, cussoside E were isolated from the dried leaves of Cussonia racemosa, along with two known flavonol glycosides identified as rutin and kaempferol rutinoside. The structures of the compounds were deduced on the basis of their physical and spectral data.

Five new flavonol glycosides (1, 3, 5-7) were isolated from the aerial parts of Epimedium pubescens Maxim., along with two known compounds, sagittasine C (2) and 4',5-dihydroxyl-8-(3,3-dimethylallyl)-flavonol 3-O-[β-D-xylopyranosyl(1→3)-4-O-acetyl-α-L-rhamnopyranoside]-7-O-β-D-glucopyranoside (4). The structures were elucidated on the basis of their 1D-, 2D-NMR, MS, UV and IR spectra data.

A new flavonol triglycoside, rhamnocitrin-3-O-neohesperoside-4'-O-glucoside was isolated from the ethanol extract of Cadaba glandulosa together with two known diglycosides rhamnocitrin-3-O-neohesperoside and rhamnetin-3-neohesperoside. Characterization of the three compounds was achieved by various spectroscopic methods.