The aim of the study was to investigate how the fine particle content of lactose carriers prepared with different types of lactose fines regulates dry powder inhaler (DPI) formulation performance of a cohesive batch of micronised budesonide. Budesonide formulations (0.8 wt%) were prepared with three different lactose carriers (Lactohale (LH) LH100, 20 wt% LH210 in LH100 and 20 wt% LH300 in LH10...

The present study deals with the utilization of fines generated from comminution process (crushing, grinding and screening) of the Run of Mines into value added products i.e. fluxed iron ore pellets. The study comprises to understand the physical and mechanical behavior of five distinguished chemical compositions of green and dried iron ore pellets with respect to a typical Mini Blast furnace (...

This study provides, for the first time, an evaluation of the physicochemical properties of batch cooling crystallized mannitol particles combined with how these properties correlated with the inhalation performance from a dry powder inhaler (Aerolizer). The results showed that the type of polymorph changed from β-form (commercial mannitol) to mixtures of β+ δ-mannitol (cooling crystallized man...

This article argues that it is doubtful that the fivefold increase in maximum fines under New Zealand’s Health and Safety in Employment Amendment Act 2002 will be successful in providing suitable precautionary incentives. Expected penalties remain at relatively low levels, with the continued use of capped fines along with substantial margins for deterrence of the most serious cases. On average,...

Using a fast X-ray tomography setup measurements have been done on a 25 cm diameter f luidized bed of Geldart B pow^der and a 24 cm bed of Geldart A powder. The average bubble sizes have been determined over a measurement period of 60 seconds. The resolution of this setup is about 4.5 m m per pixel at a rate of 250 reconstructions per second. I t is possible to detect bubbles as small as 2.5 cm...

The present paper reports a statistical analysis of the performance of the blast furnace number X at the Bhilai Steel Plant over a period of sixteen years with the special reference to the quality and consumption of sinter . The variation in basicity and consumption of sinter, for the blast furnace data considered , is wide. The range of data covers high level to almost nil amount of raw limest...

A mobile, low-field nuclear magnetic resonance (NMR) sensor for onboard, inline detection of catalytic fines in fuel oil in the shipping industry is presented as an alternative to onshore laboratory measurements. Catalytic fines (called cat fines) are aluminosilicate zeolite catalysts utilized in the oil cracking process at refineries. When present in fuel oil, cat fines cause abrasive wear of ...

Instability of liquefaction is one of the major reasons which results in the failure of earth structure such as dam. The present study focuses on the simulation of static liquefaction behavior for granular materials such as sand and sand-silt mixtures. Based on micromechanical analysis of inter-particle behavior, a simple one-scale model is proposed to simulate the stress-strain response of san...

In this review article, the authors present up-to-date developments on experimental, modeling and field studies on the role of subsurface colloidal fines on contaminant transport in saturated porous media. It is a complex phenomenon in porous media involving several basic processes such as colloidal fines release, dispersion stabilization, migration and fines entrapment/plugging at the pore con...

The sharp, nonoverlapping Raman bands for plagioclase, pyroxene, and olivine would be advantageous for on-surface, active mineralogical nalysis of lunar materials. A robust, light-weight, low-power, over-based Raman spectrometer with a laser exciting source, entirely transmission-mode holographic optics, and a charge-coupled device (CCD) detector could fit within a <20 cm cube. A sensor head on...