Fine excipient particles or 'fines' have been shown to improve the dispersion performance of carrier-based formulations for dry powder inhalation. Mechanistic formulation studies have focussed mainly on explaining this positive effect. Previous studies have shown that higher drug contents may cause a decrease in dispersion performance, and there is no reason why this should not be true for fine...

To determine if deoxynivalenol (DON) is concentrated in small corn screenings, fourteen to twenty-three 1.1 kg test samples were taken from each of 10 barges of shelled corn. Each of the 181 test samples was divided into 2 components (fines and clean) using a 5 mm screen. The clean component sample rode the 5 mm screen and the fines component sample passed through the 5 mm screen. The DON conce...

Using a dataset of over 1.6 million inspections by the Occupational Safety and Health Agency (OSHA) from 1990 through 2010, we explore the determinants of inspection and enforcement outcomes. OSHA is an institutionally split agency, with the federal agency conducting inspections in 25 states and state agencies conducting inspections in the remaining 25. The geographic variety and range over 21 ...

The diterpenes cafestol and kahweol are present in unfiltered coffee in oil droplets and floating fines. They elevate serum cholesterol and alanine aminotransferase (ALT). We measured fines in coffee brews, and examined diterpene availability from spent grounds in healthy volunteers. Turkish or Scandinavian boiled coffee contained 2-5 g fines/L and French press coffee contained 1.5 g fines/L. A...

PURPOSE This study examined federal and state civil money penalties and fines collected from nursing homes and how states used the collected funds. DESIGN AND METHODS We used a telephone survey of state officials, Freedom of Information Act requests, state Web site searches, and stakeholder interviews to describe the funds collected, the availability and the use of funds, public information a...

Cone penetration resistance in sands with fines contents up to 35% is explored through drained cylindrical cavity expansion simulations with a modified MIT-S1 constitutive model. The constitutive model is calibrated to sands with 0%, 10%, 20%, and 35% low-plasticity fines with data from constant volume direct simple shear, drained and undrained triaxial compression, shear wave velocity, and 1D-...

The interaction of chemical dispersants and suspended sediments with crude oil influences the fate and transport of oil spills in coastal waters. A wave tank study was conducted to investigate the effects of chemical dispersants and mineral fines on the dispersion of oil and the formation of oil-mineral-aggregates (OMAs) in natural seawater. Results of ultraviolet spectrofluorometry and gas chr...

Syrian petroleum coke, produced by a delayed coking unit, is characterized by a high percentage of fines which tends to reduce its commercial value. Blending coke fines using appropriate binders, such as bitumen and polyacrylic acid, can lead, however, to an improved coke that is similar in structure, appearance and other properties to better-quality coke lumps. In this work, samples of Syrian ...

We study the use of fines and inspections to control production activities that create external damages. The model contains a continuum of firms, differing in their compliance costs, so that only high-cost firms evade the regulations. If fines are low, then Pigouvian rules for taxing externalities apply, modified to account for costly inspections. According to Becker’s classic work on crime and...

Long term success of rehabilitation on bauxite-processed residue storage areas is dependant on establishing a capping stratum which will satisfy water use and nutrient cycling requirements of the intended plant community. Bauxite residue sand is the primary growth media for rehabilitating residue disposal areas (RDAs) in Western Australia however; the sustainability of the vegetation cover can ...