CONTEXT Despite increasing awareness about the potential impact of financial conflicts of interest on biomedical research, no comprehensive synthesis of the body of evidence relating to financial conflicts of interest has been performed. OBJECTIVE To review original, quantitative studies on the extent, impact, and management of financial conflicts of interest in biomedical research. DATA SO...

BACKGROUND Clinical practice guidelines (CPG) are developed, endorsed, and disseminated through professional medical organizations such as the American Psychiatric Association (APA) as the standard of care for health care providers. Because of their influence, it is critical that CPG are based on objective data, unprejudiced by stakeholder groups, and that any financial associations between aut...

BACKGROUND Increasing attention has been given to the transparency of potential conflicts of interest in clinical medicine and biomedical sciences, particularly in journal publishing and science advisory panels. The authors examined the degree and type of financial ties to the pharmaceutical industry of panel members responsible for revisions of the Diagnostic and Statistical Manual of Mental D...

CONTRIBUTORS Irina Leonova, Financial Economist, Division of Market Oversight, Commodity Futures Trading Commission David Taylor, Special Counsel, Division of Market Oversight, Commodity Futures Trading Commission Alan Deaton, Chief of Data Strategy Section, Division of Insurance and Research, Federal Deposit Insurance Corporation Mark Montoya, Senior Business Analyst, Federal Deposit Insurance...

This paper illustrates the application of a developed global fund reporting ontology (GFRO) for efficient financial reporting. The GFRO extends Financial Industry Business Ontology (FIBO). Existing reporting financial information systems lack the ability to integrate data from heterogenic sources and provide unified and consistent financial reports that will comply with regulations. This study ...

a r t i c l e i n f o In this study, the advanced panel threshold regression model was used to test whether a marginal threshold value representing optimal financial decisions exists respective to the holding ratio of free cash flow, the debt ratio, and the dividend payout ratio determined by the U.S. life and property–casualty insurance industry. The results indicated that an optimal financial...