In the eggs of the newt, Triturus pyrrhogaster, 2 separate factors are recognized which take part in cleavage furrow formation. (1) The inductive capacity for the furrow formation by the cytoplasm lying under the cortex along the cleavage furrow (FIC); and (2) the reactivity of the overlying cortex to form a furrow in response to FIC. (1) FIC. The inductive capacity is shown by the fact that FI...

OBJECTIVE To collect, preserve and document primary ethnopharmacological information on common natural remedies (NRs) used by the Chinese community to treat and/or manage common diseases in Mauritius, a tropical multicultural island in the Indian Ocean. METHODS Face-to-face interviews were carried out with 52 key Chinese informants using a semi-structured questionnaire. Quantitative ethnobota...

In this paper we present an overview of the possibilities of the finite increment calculus (FIC) approach for deriving computational methods in mechanics with improved numerical properties for stability and accuracy. The basic concepts of the FIC procedure are presented in its application to problems of advection-diffusion-reaction, fluid mechanics and fluid-structure interaction solved with th...

BACKGROUND Whether and how research training programs contribute to research network development is underexplored. The Fogarty International Center (FIC) has supported overseas research training programs for over two decades. FIC programs could provide an entry point in the development of research networks and collaborations. We examine whether FIC's investment in research training contributed ...

Protein AMPylation, the transfer of AMP from ATP to protein targets, has been recognized as a new mechanism of host-cell disruption by some bacterial effectors that typically contain a FIC-domain. Eukaryotic genomes also encode one FIC-domain protein,HYPE, which has remained poorly characterized.Here we describe the structure of human HYPE, solved by X-ray crystallography, representing the firs...

The failure of the information-based Akaike Information Criterion (AIC) in the context of singular models can be rectified by the definition of a Frequentist Information Criterion (FIC). FIC applies a frequentist approximation to the computation of the model complexity, which can be estimated analytically in many contexts. Like AIC, FIC can be understood as an unbiased estimator of the model pr...

As a structure-based image compression technology, fractal image compression (FIC) has been applied not only in image coding but also in many important image processing algorithms. However, two main bottlenecks restrained the develop and application of FIC for a long time. First, the encoding phase of FIC is time-consuming. Second, the quality of the reconstructed images for some images which h...

The ubiquitous FIC domain is evolutionarily conserved from bacteria to human and has been shown to catalyze AMP transfer onto protein side-chain hydroxyl groups. Recently, it was predicted that most catalytically competent Fic proteins are inhibited by the presence of an inhibitory helix αinh that is provided by a cognate anti-toxin (class I), or is part of the N- or C-terminal part of the Fic ...

level Academic scien�fic community Concrete project level Industry community Data level Academic scien�fic community Validity criterion Ontological appropriateness