A variety of developmental defects occur as a result of prenatal exposure to alcohol (ethanol) in utero. In humans [5], those defects are collectively classified as Fetal Alcohol Spectrum Disorders, with Fetal Alcohol Syndrome [6] (FAS) representing the more severe defects. FAS is defined by preand post-natal growth retardation [7], minor facial abnormalities, and deficiencies in the central ne...

A variety of developmental defects occur as a result of prenatal exposure to alcohol (ethanol) in utero. In humans [5], those defects are collectively classified as Fetal Alcohol Spectrum Disorders, with Fetal Alcohol Syndrome [6] (FAS) representing the more severe defects. FAS is defined by preand post-natal growth retardation [7], minor facial abnormalities, and deficiencies in the central ne...

context maternal serum human chorionic gonadotropin (hcg) and alpha fetal protein (afp) were originally introduced to detect trisomy 21 and neural tube defects. however, in the absence of aneuploidy or neural tube defects, mid-trimester maternal serum hcg and/or maternal serum afp associated with adverse pregnancy outcomes. pregnancies with unexplained mid-trimester elevation in maternal serum ...

A variety of developmental defects occur as a result of prenatal exposure to alcohol (ethanol) in utero. In humans [5], those defects are collectively classified as Fetal Alcohol Spectrum Disorders, with Fetal Alcohol Syndrome [6] (FAS) representing the more severe defects. FAS is defined by preand post-natal growth retardation [7], minor facial abnormalities, and deficiencies in the central ne...

A variety of developmental defects occur as a result of prenatal exposure to alcohol (ethanol) in utero. In humans [5], those defects are collectively classified as Fetal Alcohol Spectrum Disorders, with Fetal Alcohol Syndrome [6] (FAS) representing the more severe defects. FAS is defined by preand post-natal growth retardation [7], minor facial abnormalities, and deficiencies in the central ne...

OBJECTIVE To examine the significance of fetal nuchal translucency at 10-14 weeks' gestation in the prediction of abnormal fetal karyotype. DESIGN Prospective screening study. SETTING The Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London. SUBJECTS 827 fetuses undergoing first trimester karyotyping by amniocentesis or chorionic villus sampling. MAIN OU...

We present our experience in the contribution of three-dimensional ultrasonography, using the rendering mode, to the prenatal diagnosis of congenital anomalies including neurological defects (acrania/anencephaly, encephalocele, holoprosencephaly), facial anomalies (cyclopia and facial clefts), abdominal wall defects (omphalocele and gastroschisis) and defects of extremities (fetal muscle-skelet...