background: the task force on plants for fertility regulation in men continued with its program to identify novel prototypes in plants alleged to have fertility regulating properties. nigella sativa   objective: to evaluated the role of alcoholic extract of nigella sativa on fertility potential, pituitary-testicular axis hormones and testosterone in male rats.   materials and methods: 24 male r...

Males and females require different patterns of pituitary gonadotropin secretion for fertility. The mechanisms underlying these gender-specific profiles of pituitary hormone production are unknown; however, they are fundamental to understanding the sexually dimorphic control of reproductive function at the molecular level. Several studies suggest that ERK1 and -2 are essential modulators of hyp...

IN the two preceeding papers (Sinnathuray, Med. J. Malaysia, 1979), which represent the first two parts of my inaugural address, the impacts of reproductive research on Maternal Health (Part I) and on Fetal Health (Part II) have been presented at some length. In this paper is presented the impact of reproductive research on Fertility Health, and it covers the last two areas of my inaugural addr...

Maintenance of normal male fertility relies on the process of spermatogenesis which is under complex endocrine control by mechanisms involving gonadotropin and steroid hormones. Although testosterone is the primary sex steroid in males, estrogen is locally produced in the testis and plays a very crucial role in male fertility. This is evident from presence of both the estrogen receptors alpha (...

Male fertility is a very important but often neglected area in medical practice. Compared to what available on female subfertility, there dearth research male fertility. Fertility depends the normally functioning hypothalamopituitary gonadal axis, normal testis and environment necessary for viable, motile sperm production. The production of healthy germ cells require temperature which slightly ...